Publications by authors named "David Rozenblat"

Background: Combination therapy with a beta-lactam and an aminoglycoside is currently recommended for the empirical treatment of urosepsis. Nephrotoxicity is the most common adverse effect of aminoglycosides and acute kidney injury (AKI) has a significant prognostic impact in septic shock. This study aimed to evaluate the impact of empirical antibiotic therapy with or without an aminoglycoside on survival and renal outcomes in patients admitted to the intensive care unit (ICU) with urosepsis.

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Article Synopsis
  • Renal complications are common in cancer patients, leading to the emergence of onco-nephrology, a subspecialty that focuses on this intersection, although its scope is not well defined.
  • A study conducted through anonymous online surveys gathered insights from 228 physicians, revealing that nephrologists and oncologists felt moderately confident (around 6/10) in handling onco-nephrological cases, but many believed their training and resources were inadequate.
  • The results highlighted a significant demand for better resources and guidelines, leading to the establishment of a national working group, GRIFON, to address these gaps in onco-nephrology practice in France.
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