Therapeutic Duel of Rifaximin Versus Lactulose in Hepatic Encephalopathy: A Systematic Review.

This systematic review aimed to compare the clinical efficacy of rifaximin versus lactulose in the management of hepatic encephalopathy (HE) by analyzing evidence from randomized controlled trials (RCTs). A comprehensive search across major databases identified seven eligible RCTs encompassing 693 adult patients diagnosed with overt or minimal HE. Findings demonstrated that rifaximin is at least as effective as lactulose in reversing HE symptoms, with some studies reporting significantly higher HE reversal rates when rifaximin was used in combination with lactulose (e.

The Impact of Intraoperative Imaging on Outcomes in Combined Neurosurgical and Reconstructive Procedures: A Systematic Review.

This systematic review evaluates the impact of intraoperative imaging on surgical outcomes in combined neurosurgical and reconstructive procedures. A comprehensive literature search was conducted across four databases, including PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL), focusing on clinical trials published between 2019 and 2024. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, six studies that met stringent eligibility criteria were selected, including randomized controlled trials (RCTs) and prospective cohort studies involving imaging modalities such as intraoperative MRI (iMRI), intraoperative ultrasound (iUS), fluoroscopy, neuronavigation, and machine vision-based systems.

Multidisciplinary Surgical Management of Concurrent Traumatic Brain and Abdominal Injuries: A Systematic Review of Integrated Care Approaches and Clinical Outcomes.

This systematic review explores the impact of multidisciplinary surgical management on clinical outcomes in patients with concurrent traumatic brain and abdominal injuries, two of the most life-threatening forms of polytrauma. By analyzing evidence from recent observational studies, expert consensus, and systematic reviews, this study highlights the clinical relevance of coordinated multidisciplinary care. The available evidence, though limited, suggests that early and integrated surgical intervention may improve survival rates, reduce ICU admissions and length of stay, and enhance neurological recovery.