Bioprospection of Phytotoxic Plant-Derived Eudesmanolides and Guaianolides for the Control of , , and Weeds.

The phytotoxicities of a selection of eudesmanolides and guaianolides, including natural products and new derivatives obtained by semisynthesis from plant-isolated sesquiterpene lactones, were evaluated in bioassays against three weeds of concern in agriculture ( L., L., and L.

Evaluation of the phytotoxic and antifungal activity of C -sesquiterpenoids as potential biopesticides.

Background: Natural products are a promising source for the development of new pesticides with alternative mechanisms of action. In this study, we evaluated the phytotoxic and antifungal activity of a novel family of natural C -sesquiterpenoids and performed a study of the effect caused by the elimination of the α-methylene-γ-butyrolactone system and its importance to their biological activity.

Results: Many tested compounds exhibited a strong phytotoxic activity.

Synthesis of Pertyolides A, B, and C: A Synthetic Procedure to C-Sesquiterpenoids and a Study of Their Phytotoxic Activity.

C-sesquiterpenoids are a group of natural products that have been recently discovered. These compounds have the peculiarity of lacking the α,β-methylene butyrolactone system, which is known to be quite relevant for many of the biological activities reported for sesquiterpene lactones. Unfortunately, the biological interest of C-sesquiterpenoids has not been studied in-depth, mainly due to the poor isolation yields in which they can be obtained from natural sources.

Synthesis of Vlasouliolides: A Pathway toward Guaiane-Eudesmane C/C Dimers by Photochemical and Michael Additions.

is a plant found in China used in traditional medicine. Recent isolation studies have led to the discovery of vlasouliolides, which are natural sesquiterpene dimers. However, the yields obtained from isolation have proven to be really low (<0.