Publications by authors named "David C McCarthy"

Article Synopsis
  • EEG is crucial for diagnosing and managing neurologic issues like seizures and brain injuries in veterans, prompting a study on the infrastructure of EEG services within the Veterans Administration (VA).
  • A survey sent to 123 VA hospitals revealed that while most had EEG services, only a minority offered continuous EEG, and many facilities reported a lack of adequate resources such as EEG technologists and machines.
  • The study indicates significant variability in EEG infrastructure and highlights that expanding tele-EEG services could improve access and patient management in resource-limited environments.
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Children comprise approximately 22% of the population in the United States.1 In a widespread disaster such as a hurricane, pandemic, wildfire or major earthquake, children are at least proportionately affected to their share of the population, if not more so. They also have unique vulnerabilities including physical, mental, and developmental differences from adults, which make them more prone to adverse health effects of disasters.

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Introduction: Botulinum toxin (BTX) has been used to treat muscle overactivity and can reduce pain from muscle spasm. There are no previous reports to our knowledge of using BTX to treat the pain from intractable focal motor seizures.

Case Report: We present a case of chronic, focal, muscle pain, and spasm secondary to intractable focal motor seizures treated with BTX.

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Fatigue and excessive daytime sleepiness are common symptoms in patients with neurological injury. Modafinil has been shown to ameliorate these symptoms, but its use in patients with seizures has been limited because of safety concerns. Using a large centralized clinical registry, we performed a retrospective chart review of patients with a diagnosis of epilepsy who were given modafinil over a 10-year period.

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Functional magnetic resonance imaging (fMRI) of the human brain has shown that the hippocampus and the left temporal and frontal cortices play a key role in the formation of new verbal memories. We recorded electrical activity from 2349 surgically implanted intracranial electrodes in epilepsy patients while they studied and later recalled lists of common words. Using these recordings, we demonstrate that gamma oscillations (44-64 Hz) in the hippocampus and the left temporal and frontal cortices predict successful encoding of new verbal memories.

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