Growth Kinetics of Venous Tumor Thrombus from Renal Cell Carcinoma.

Purpose: Renal cell carcinoma (RCC) is known to form venous tumor thrombus (VTT); however, limited data exist on VTT growth rates. We sought to characterize the growth rate of VTTs from RCC and identify clinicopathologic features associated with faster thrombus growth.

Materials And Methods: Systemic therapy naïve patients with RCC and VTT with two pre-operative imaging studies performed with contrast at least 7 days apart were identified from a single institutional registry.

The impact of prophylactic incisional negative pressure wound therapy on surgical site infection following open radical cystectomy.

Purpose: Surgical site infection (SSI) following open radical cystectomy (ORC) is common and carries significant morbidity. Incisional negative pressure wound therapy (iNPWT) has not been rigorously studied in this population. Herein, we evaluate the association between prophylactic iNPWT and postoperative wound complications in ORC patients.

Characterizing the Hospital Caseload-Outcome Relationship for Radical Nephrectomy With Inferior Vena Cava Tumor Thrombectomy: Analysis From the National Inpatient Sample.

Objective: To characterize hospital complications following radical nephrectomy (RN) for renal cell carcinoma (RCC) with inferior vena cava (IVC) and cardiac venous tumor thrombectomy (VTT) and evaluate the relationship between hospital caseload and patient outcomes.

Methods: A pooled, cross-sectional analysis was conducted using data from the 2016-2020 National Inpatient Sample (NIS) database. Patients undergoing RN for RCC with IVC- or cardiac-VTT were identified, and complications were categorized using an approximation of the Clavien system.

Transrectal bladder prolapse in a male managed with a robotic-assisted laparoscopic cystoprostosacropexy.

Pelvic floor disorders frequently occur as the result of excessive straining from chronic constipation or the trauma of vaginal childbirth, making them more common in women. We present a 62-year-old male with bladder prolapse through the anterior rectal wall in the setting of longstanding bladder holding behavior and excessive straining to void. We performed a novel robotic-assisted laparoscopic cystoprostosacropexy by anchoring the bladder and prostate to the sacrum to prevent bladder descent.

Oncologic control and predictors of urologic reconstruction after Mohs micrographic surgery for low-risk penile malignancy.

Purpose: Mohs micrographic surgery (MMS) is a low-risk penile cancer management option. However, contemporary patients' short-term oncologic control and preoperative characteristics predicting reconstruction needs are undefined. This study assesses MMS's oncologic efficacy for low-risk penile cancer and identifies baseline predictors of post-resection reconstruction referral.

Pathologic and survival outcomes following radical cystectomy for "progressive" and "de novo" muscle-invasive bladder cancer: A meta-analysis stratified by neoadjuvant chemotherapy status.

Objective: To compare survival and pathologic outcomes in patients with progressive muscle-invasive bladder cancer (pgMIBC) and de novo muscle-invasive bladder cancer (dnMIBC) after radical cystectomy (RC), with a focus on the role of neoadjuvant chemotherapy (NAC).

Methods: A comprehensive literature search was conducted on PubMed and EMBASE databases to identify studies comparing pgMIBC to dnMIBC. Survival outcomes, including cancer-specific survival (CSS), overall survival (OS), and recurrence-free survival (RFS), and pathologic outcomes (rates of ≤pT1, pT0, pT3/T4, and pN+ disease) were compared between pgMIBC and dnMIBC.

Diminished Short-Term Efficacy of Reduced-Dose Induction BCG in the Treatment of Non-Muscle Invasive Bladder Cancer.

The ongoing Bacillus Calmette-Guérin (BCG) shortage has created challenges for the treatment of non-muscle invasive bladder cancer (NMIBCa). Our objective was to evaluate the efficacy of reduced-dose induction BCG (RD-iBCG) compared to full-dose induction BCG (FD-iBCG) regarding recurrence rates. We hypothesized that patients receiving RD-iBCG may recur at a higher rate compared to those who received FD-iBCG therapy.

Prognostic significance of sarcomatoid features in metastatic renal cell carcinoma treated with cytoreductive nephrectomy and targeted therapy.

Introduction: The presence of sarcomatoid features in localized renal cell carcinoma (RCC) is associated with worse outcomes. We sought to use a national database to evaluate the outcomes and prognosis of metastatic RCC (mRCC) with sarcomatoid features treated with cytoreductive nephrectomy (CN) and targeted therapy (TT).

Methods: The National Cancer Database (2010-2013) was used to identify patients with mRCC at diagnosis.

Role of Hysteropexy in the Management of Pelvic Organ Prolapse.

Purpose Of Review: To discuss considerations for hysteropexy for apical pelvic organ prolapse (POP) and summarize available literature comparing various hysteropexy techniques to analogous procedures involving hysterectomy.

Recent Findings: Hysteropexy for apical POP has increased in popularity in recent years, although anatomic factors and gynecologic cancer risk must be taken into account. Native tissue hysteropexy options include the LeFort colpocleisis, sacrospinous hysteropexy, and uterosacral hysteropexy.