Internal structure of the action and acceptance questionnaire II (AAQ-II): evidence for a three-factor and bifactor model in two samples of university students.

Background: Experiential avoidance (EA), defined as an inflexible behavioral pattern by which a person tries to avoid contact with private unpleasant situations, is considered a transdiagnostic variable associated with various psychopathological disorders. The Acceptance and Action Questionnaire II (AAQ-II) is a broadly used measure of EA. However, inconsistencies in the methods employed for examining its internal structure and the need for culturally validated measures in diverse populations highlight the need for further study.

COVID-19 Vaccine-Induced Rhabdomyolysis in a 53-Year-Old Woman.

Introduction: COVID-19-induced rhabdomyolysis is a common complication in COVID-19 infection. However, only a handful of cases have been reported showing links between COVID-19 vaccine and rhabdomyolysis.

Case Presentation: We present the case of a 53-year-old woman, who recently received COVID-19 vaccine and presented to the hospital with progressive extremity weakness.

Childhood adversities and depression according to sexual orientation and gender identity among university students in Chile.

Childhood adversities (CA) are a recognized risk factor for depression. However, research on how these adversities differ based on sexual orientation and gender identity remains limited. This study aimed to examine differences in the type, number, and frequency of CA and analyze their association with depression according to sexual orientation and gender identity among university students in Chile.

Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative.

Background: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students.

Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023.

Childhood adversities and their associations with mental disorders in the World Mental Health International College Student surveys initiative.

Purpose: This study investigates associations of childhood adversities (CAs) with lifetime prevalence, 12-month prevalence, and 12-month persistence of mental disorders in a large cross-national sample of university students.

Methods: Data came from epidemiologic surveys carried out by the World Mental Health International College Student (WMH-ICS)Initiative across 18 countries (n=60,719). The web-based surveys screened for lifetime and 12-month prevalence and age-of-onset of common DSM-5 disorders (Major Depressive Disorder, Bipolar I/II Disorder, Generalized Anxiety Disorder, Panic Disorder, Posttraumatic Stress Disorder, Alcohol and Drug Use disorders, Attention-Deficit/Hyperactivity Disorder) and five types of CAs (family dysfunction, emotional abuse, physical abuse, sexual abuse, neglect).

Bridging Sectors and Disciplines to Gain a Critical Understanding of the Eco-Social Determinants of Health Inequities: The ESDHI-EU Conference.

The current eco-social crisis is driven by an unsustainable socioeconomic model based on continued economic growth that exceeds planetary limits. Groups experiencing disadvantages are being disproportionately affected, further deepening global, regional, and local health inequities. Understanding the simultaneous ecological and social crises through a comprehensive approach across disciplines and sectors-including citizen participation-is essential for driving transformative change and paradigm shifts.

Prevalence, age-of-onset, and course of mental disorders among 72,288 first-year university students from 18 countries in the World Mental Health International College Student (WMH-ICS) initiative.

Background: The college years are a developmentally sensitive period for mental disorder onset. Reliable epidemiological data are critical for informing public health responses. This study aimed to estimate prevalence and socio-demographic distributions of common DSM-5 mental disorders among first-year university students from 77 universities across 18 countries.

Interventions to Reduce Mental Health Stigma in Young People: A Systematic Review and Meta-Analysis.

Importance: Mental health stigma is a considerable barrier to help-seeking among young people.

Objective: To systematically review and meta-analyze randomized clinical trials (RCTs) of interventions aimed at reducing mental health stigma in young people.

Data Sources: Comprehensive searches were conducted in the CENTRAL, CINAHL, Embase, PubMed, and PsycINFO databases from inception to February 27, 2024.

Effect of prior beliefs and cognitive deficits on learning in first-episode schizophrenia patients.

Introduction: It is known that cognitive deficits are a core feature of schizophrenia and that in the general population, prior beliefs significantly influence learning and reasoning processes. However, the interaction of prior beliefs with cognitive deficits and their impact on performance in schizophrenia patients is still poorly understood. This study investigates the role of beliefs and cognitive variables (CVs) like working memory, associative learning, and processing speed on learning processes in individuals with schizophrenia.

Internal consistency and temporal stability of the Community Assessment of Psychic Experiences (CAPE): A reliability generalization meta-analysis.

Psychotic experiences (PE) are prevalent in general and clinical populations and can increase the risk for mental disorders in young people. The Community Assessment of Psychic Experiences (CAPE) is a widely used measure to assess PE in different populations and settings. However, the current knowledge on their overall reliability is limited.

Development of a Multiplatform Tool for the Prevention of Prevalent Mental Health Pathologies in Adults: Protocol for a Randomized Control Trial.

Background: The prevalence of depression and anxiety has increased in recent years, with many individuals having trouble accessing mental health support. Smartphones have become an integral part of modern life, with apps offering new ways to deliver evidence-based self-help strategies to cope with common mental health symptoms. However, most of them do not have empirical evidence of their overall effectiveness or the effectiveness of their components, which could pose a risk for users.

Psychometric evidence of the Acceptance and Action Questionnaire-II (AAQ-II): an item response theory analysis in university students from Chile.

Background: Experiential avoidance (EA) is a psychological mechanism associated with several mental health disorders and is regarded as a relevant target by third-generation cognitive behavioral therapies. It has been mainly assessed through self-report questionnaires, and the AAQ-II is the most used tool. Its psychometric evidence has been mostly tested through the classical test theory (CTT) and very scarcely assessed through Item Response Theory (IRT).

Initial validation of the International Trauma Questionnaire (ITQ) in a sample of Chilean adults.

Background: ICD-11 Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD) are stress-related disorders. The International Trauma Questionnaire (ITQ) is a widely used instrument to assess PTSD and CPTSD. To date, there is no evidence of the psychometric characteristics of the ITQ in Latin American countries.

Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy.

Chimeric antigen receptor (CAR) T cells targeting CD19 B cells have demonstrated efficacy in refractory systemic lupus erythematosus (SLE). Although initial clinical data suggest that anti-CD19 CAR T cell therapy is well tolerated and highly effective, the immunologic consequences of CAR T cell therapy in SLE patients remain unclear. We profiled serum in six refractory SLE patients prior to and 3 months following CAR T cell infusion.

Development and validation of a software application to analyze thermal and kinematic multimodels of Stirling engines.

The work developed presents, for the first time, a tool to analyze all the thermodynamic models used in the study and development of Stirling engines: isothermal, ideal adiabatic and adiabatic with losses, combined adiabatic thermodynamic with finite speed (CAFS), thermodynamic with finite speed (FST), ideal polytropic and polytropic with losses (PSVL), allowing a comparative study of them. This software (ASCE-UMA), designed and implemented in a Matlab GUI® allows to obtain the operating parameters of these engines, calculating the thermodynamic parameters, power output and efficiency. Additionally, the thermodynamic models can be evaluated with different mechanical configurations, for which different drive mechanisms are implemented: Sinusoidal, Alfa Ross yoke types, Alfa Ross V yoke, Beta rhombic type and free piston Stirling engine (FPSE).

Mutations in the bZip region of the CEBPA gene: A novel prognostic factor in patients with acute myeloid leukemia.

Background: Hematopoiesis, the process of blood cell formation involves on a complex network of transcription factors. Among them, the CCAAT-enhancer-binding protein alpha (CEBPA) plays a crucial role in maintaining the balance between myeloid proliferation and differentiation. Imbalances in this network can lead to disrupted differentiation and contribute to the development of malignant diseases.

Initial validation of the Multidimensional Adolescent Functioning Scale (MAFS) in Spanish-speaking students from Chilean secondary schools.

Introduction: Psychosocial functioning is closely associated with psychopathology and wellbeing in different populations, particularly adolescents. Despite its relevance, measures assessing psychosocial functioning in healthy adolescents are scant as most focus on adults or clinical populations. We evaluated the psychometric properties of the Multidimensional Adolescent Functioning Scale (MAFS), a self-report questionnaire created to assess three dimensions of psychosocial functioning ('general functioning', 'family-related functioning', and 'peer-related functioning') in adolescents from the general population.