Photothermal/GSH-dual-responsive organic quantum dots enabling traceable DNA delivery.

Quantum dots, with their superior intrinsic fluorescence and photostability, are emerging as a promising option for cancer gene therapy, diagnosis, and imaging. However, low gene delivery efficiency, insufficient targeting, and responsiveness remain challenges. To address these issues, PEI-based carbon quantum dots (CPNCs) were constructed by crosslinking polyethylenimine quantum dots (PQDs) with carbon quantum dots (CQDs) via disulfide bonds.

Data-free knowledge distillation via text-noise fusion and dynamic adversarial temperature.

Data-Free Knowledge Distillation (DFKD) have achieved significant breakthroughs, enabling the effective transfer of knowledge from teacher neural networks to student neural networks without reliance on original data. However, a significant challenge faced by existing methods that attempt to generate samples from random noise is that the noise lacks meaningful information, such as class-specific semantic information. Consequently, the absence of meaningful information makes it difficult for the generator to map this noise to the ground-truth data distribution, resulting in the generation of low-quality training samples.

Palladium-Catalyzed Coupling of Aryl Iodides with Sulfinamide Reagents for the Construction of Sulfinamides.

A novel sulfinamide reagent was developed that enables the one-step installation of sulfinamides through palladium-catalyzed coupling with aryl iodides. This method offers distinct advantages, including the use of readily available starting materials and broad substrate compatibility. Moreover, the strategy was successfully extended to the synthesis of complex functional molecules.

[Study on mechanical properties of through-the-scope airway stents and complications caused by TTS airway stents in rabbits trachea].

The TTS(through-the-scope)airway stent is a novel self-expanding nitinol alloy metal stent. Its structure and method of implantation differ significantly from those of the traditional OTW(over-the-wire)stent. In this study, we compared the mechanical properties of the TTS and OTW stents, and both of which were implanted into the tracheas of rabbits to compare the differences in complications caused by these two types of stents.

Effects and Mechanisms of Lactiplantibacillus plantarum G83 on Enterotoxigenic Escherichia coli (ETEC)-Induced Intestinal Inflammation.

Enterotoxigenic Escherichia coli (ETEC) is a prevalent intestinal pathogen that significantly impacts both human and animal health. G83, isolated from giant panda feces, has demonstrated notable probiotic properties. In this study, C57BL/6 J mice were randomly divided into Control, ETEC, and G83 groups.