International Multicentre Study on the Treatment of Infrarenal Penetrating Aortic Ulcers.

Objective: This study aimed to evaluate treatment indications, compare therapeutic approaches, and assess outcomes in patients with infrarenal penetrating aortic ulcers (iPAUs).

Methods: This was a retrospective, multicentre, observational study of patients with iPAUs treated between January 2018 and December 2022 across 12 European centres. Treatment strategies included open surgical repair (OSR) and endovascular techniques, including balloon expandable stent grafts (BESGs), covered endovascular reconstruction of the aortic bifurcation (CERAB), and endovascular aortic repair (EVAR) using bifurcated or tube grafts.

Socioeconomic vulnerability and osteoporosis treatment disparities during COVID-19 lockdown among U.S. medicare enrollees who initiated romosozumab.

Unlabelled: Higher area socioeconomic level was associated with a decreased risk of romosozumab discontinuation during COVID-19 lockdown among U.S. Medicare beneficiaries.

Operative Techniques in Mandibular Fracture Repair: A Cross-specialty Comparison of Plastic and Reconstructive Surgery, Otolaryngology, and Oral and Maxillofacial Surgery.

Background: Mandibular fractures are the most common facial fractures treated in the emergency setting, with significant variability in operative management across surgical specialties. Plastic and reconstructive surgery (PRS), otolaryngology (ENT), and oral and maxillofacial surgery (OMFS) each approach mandibular fracture repair with different philosophies, particularly regarding tooth extraction within the fracture line. However, few studies directly compare these practices.

Density-dependent network structuring within and across wild animal systems.

Theory predicts that high population density leads to more strongly connected spatial and social networks, but how local density drives individuals' positions within their networks is unclear. This gap reduces our ability to understand and predict density-dependent processes. Here we show that density drives greater network connectedness at the scale of individuals within wild animal populations.

Research burden in pediatric cancer: A mixed methods study from the PediQUEST Response Trial.

Context: Research burden in pediatric advanced cancer is understudied.

Objectives: To analyze study burden among parents and children participating in the PediQUEST Response Trial, and explore associated factors, including belonging to historically marginalized (HM) backgrounds or facing economic hardship (EH).

Methods: Mixed-methods secondary analysis of data collected for an RCT.