The Potential Impact of Ending the Ryan White HIV/AIDS Program on HIV Incidence: A Simulation Study in 31 U.S. Cities.

Background: With antiretroviral therapy, people with HIV can live a normal lifespan and not transmit HIV. The Ryan White HIV/AIDS Program provides care for over half of people with HIV in the United States.

Objective: To estimate how many HIV infections could result from cessation of Ryan White services or interruptions lasting 18 to 42 months.

Optics for broadband x-ray ptychography.

In conventional x-ray ptychography, diffraction data are collected by scanning a sample through a monochromatic and spatially coherent x-ray beam. A high-resolution image is then retrieved using an iterative algorithm. Combined with a scan of the incident photon energy, it is also possible to access chemical and elemental information.

Differential Effects of Substance Use on HIV Care and Symptom Outcomes: A Longitudinal Analysis Among People with HIV.

Among people with HIV (PWH), those with suboptimal antiretroviral therapy (ART) adherence face heightened risk for poor clinical outcomes. Substance use is a critical barrier in this population, yet most research treats substance use as a homogeneous risk factor. This study examined the differential effects of specific substances on HIV-related outcomes among PWH with suboptimal ART adherence.

In vivo 4D x-ray dark-field lung imaging in mice.

X-ray dark-field imaging is well-suited to visualizing the health of the lungs because the alveoli create a strong dark-field signal. However, time-resolved and tomographic (i.e.

3D quantification of nanolites using X-ray ptychography reveals syn-eruptive nanocrystallisation impacts magma rheology.

Nanoscale crystals are becoming increasingly recognised in the products of volcanic eruptions, spanning a range of magma compositions. The crystallisation of nanolites impacts magma rheology, ascent dynamics, and eruptive style. Their impact can be enhanced due to their capacity to aggregate and develop neighbouring chemically differentiated boundary layers.