Publications by authors named "D Sakthi"

Article Synopsis
  • Primary pulmonary synovial sarcoma (PPSS) is a rare and malignant tumor primarily affecting adolescents and young adults, characterized by specific genetic translocations.
  • A study reviewed 22 cases of PPSS, finding that the majority were monophasic tumors in male patients, with an average age of 31.5 years, and most tumors fell into grade 2 or grade 3 categories.
  • Diagnosis of PPSS can be complex, requiring a combination of clinical evaluation, histological examination, immunohistochemistry, and genetic testing to confirm the presence of specific fusion transcripts.
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Introduction: Pit and fissures are more prone to caries as compared to smooth surfaces. Sealing the pit and fissures with sealants is considered to be highly effective in the prevention of pit and fissure caries. Hydrophobic sealants are technique sensitive in nature.

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Introduction: Oral cavity harbors wide variety of microorganisms; these are considered crucial for the dental caries initiation and progression. Plaque-induced caries is a local disease; therefore, dentifrices are the most ideal vehicle for the daily delivery of antibacterial agents. In recent years, alternatives to fluorides such as green tea, probiotic, and chlorhexidine (CHX) toothpastes have been proposed to possess antiplaque and anticariogenic properties.

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Context: The incidence of colorectal cancers (CRCs) in young Indian patients is higher than the international average. CRCs in young patients are commonly of mucinous type and show microsatellite instability (MSI).

Aims: To ascertain the MSI status of mucinous CRCs in patients ≤40 years of age by molecular testing and to correlate this with immunohistochemical (IHC) analysis and tumor histology.

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Cancer is a highly intelligent system of cells, that works together with the body to thrive and subsequently overwhelm the host in order for its survival. Therefore, treatment regimens should be equally competent to outsmart these cells. Unfortunately, it is not the case with current therapeutic practices, the reason why it is still one of the most deadly adversaries and an imposing challenge to healthcare practitioners and researchers alike.

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