Tumor Absorbed Dose Predicts Survival and Local Tumor Control in Colorectal Liver Metastases Treated with 90Y Radioembolization.

Background: To evaluate predictors of outcomes in colorectal liver metastases (CLM) patients undergoing 90Y radioembolization (TARE), focusing on the impact of tumor absorbed dose.

Materials And Methods: Patients' characteristics and dosimetry assessments were analyzed in 231 patients undergoing 329 TARE sessions from 09/2009 to 07/2023. Response was assessed using RECIST1.

Inferring tephritid fly pupal development stage using non-invasive near infrared imaging and machine learning classification.

Insect pupae change morphologically (e.g., pigmentation of eyes, wings, setae and legs) during the intrapuparial period.

Immunoinformatics-guided vaccine design: A review with case study on Marburg virus.

A primary concern for world health is the emergence of new infectious diseases. Conventional vaccine development techniques are time-consuming and often limited by issues such as antigen availability and safety concerns. Immunoinformatics, a computational approach that integrates immunology and informatics, presents a promising solution for accelerating vaccine design.

Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions.

T cells recognize antigens and induce specialized gene expression programs (GEPs), enabling functions like proliferation, cytotoxicity and cytokine production. Traditionally, different T cell classes are thought to exhibit mutually exclusive responses, including T1, T2 and T17 programs. However, single-cell RNA sequencing has revealed a continuum of T cell states without clearly distinct subsets, necessitating new analytical frameworks.

Prevalence of survival without major morbidity and associated risk factors among very preterm infants: a systematic review and meta-analysis.

Introduction: Survival without major morbidity (SWMM) in very preterm infants represents a critical outcome measure in neonatal care. This systematic review evaluates both the prevalence of SWMM among infants born before 32 weeks' gestation and the associated risk factors.

Methods: We conducted a comprehensive search of PubMed, Web of Science, Embase, Cochrane Library, Scopus, CNKI, CBM, and Wanfang databases from inception through February 4, 2025.