"Chronic Cervical Midline Contusion in Rats Disrupts Aerobic, Muscular, and Cardiovascular Function".

Cardiovascular dysfunction significantly contributes to morbidity and mortality following cervical spinal cord injury (SCI). Unfortunately, only a limited number of preclinical models have been developed for investigating cardiovascular dysfunction following cervical SCI. Furthermore, the broader consequences of cervical SCI on aerobic capacity and muscle endurance during physiological stress testing also remains understudied preclinically.

Investigating the use of a one-page infographic to improve recruitment and retention to the BASIL+ randomised controlled trial: A Study Within a Trial (SWAT).

Background: Low participant recruitment and retention rates are a significant barrier to successful Randomised Controlled Trials (RCTs). A Study Within A Trial (SWAT) is an effective way to explore which trial delivery methods may be useful for improving participant recruitment and retention rates. Infographics are a useful information delivery tool that may improve participants' understanding of the trial and thus improve recruitment or retention rates.

Dog-assisted interventions to support health and wellbeing: a national survey of current practice in England.

Introduction: In England, dog-assisted interventions (DAIs) are increasingly used to support the health and wellbeing of individuals with mental and physical health conditions. Although research in this area is increasing, little is known about the national prevalence and characteristics of DAIs in practice. Advancing knowledge is important to inform development of research, policy and practice in the field.

The importance of systemic inflammatory response measurements as pretransplant risk factors for outcome after allogeneic haematopoietic cell transplantation.

Systemic inflammatory response (SIR) measures are known prognostic values in patients with solid tumours. Little is known about their impact in haematological diseases or allogeneic haematopoietic cell transplantation (alloHCT). Therefore, we evaluate the association of pretransplant inflammatory markers with the clinical outcome in a prospective analysis of alloHCT.

Inflammatory Responses Potentiate GAS M Protein Induced Cardiac Damage in an Experimental Model of Rheumatic Heart Disease.

Aim: Acute rheumatic fever (ARF) and Rheumatic heart disease (RHD) are autoimmune sequalae, that develops in a proportion of individuals exposed to group A streptococcal infection. The autoimmune pathology of ARF/RHD is multifactorial. Both host and pathogen-associated factors including genetic predisposition, inflammatory responses, tissue cross-reactive antibodies and T-cells contribute to disease development and progression.