Evaluating the Efficacy of Chemical and Herbal Endodontic Irrigants in Smear Layer Removal: An Analysis.

Aim: The current research is designed to analyze the smear layer (SL) removal efficacy of different endodontic irrigants via scanning electron microscope (SEM).

Materials And Methods: Eighty extracted premolars were gathered and allocated into four groups ( = 20) based on the array of endodontic irrigants employed: Group 1: Normal saline (NS), Group 2: 17% EDTA (Ethylenediaminetetraacetic acid), Group 3: Neem leaf extract (NLE), and Group 4: Garlic solution (GS). SL elimination was evaluated beneath SEM at upper, intermediate, and apical levels of root canals.

Evaluating the Remineralizing Potential of Dentifrices Containing Lemon Essential Oil.

Aim: The study's aim to evaluate the remineralization potential of essential oil containing dentifrices.

Materials And Methods: Thirty extracted premolars were collected and sectioned at cemento-enamel junction (CEJ) and through buccal and lingual halves. Thirty samples without cracks were embedded into acrylic blocks and examined for baseline hardness level by Vickers hardness tester (VHT).

What to Say When It Matters: Communication Skills to Address Implicit Bias Workshop.

Introduction: In academic medicine, learners, faculty, and staff commonly experience microaggressions, which have been linked to multiple negative outcomes (e.g., higher levels of depression, deteriorating well-being, increased anxiety, and feelings of isolation).

Nef defect attenuates HIV viremia and immune dysregulation in the bone marrow-liver-thymus-spleen (BLTS) humanized mouse model.

In vitro studies have shown that deletion of nef and deleterious mutation in the Nef dimerization interface attenuates HIV replication and associated pathogenesis. Humanized rodents with human immune cells and lymphoid tissues are robust in vivo models for investigating the interactions between HIV and the human immune system. Here, we demonstrate that nef deletion impairs HIV replication and HIV-induced immune dysregulation in the blood and human secondary lymphoid tissue (human spleen) in bone marrow-liver-thymus-spleen (BLTS) humanized mice.

Clinical profile of children with influenza like illness during pre-monsoon at coastal Karaikal, Puducherry, India.

Influenza infections in developing countries are under reported and WHO estimates that nearly 99% of influenza deaths worldwide occur in children under-five years of age in Asian and African countries. Consequently, this study aims to analyze the use of clinical profile and easily available laboratory parameters to aid identification of the possible viral etiology in the setting of pre-monsoon ILI. A cross-sectional study was carried out for three months among children with ILI attending fever clinic of a tertiary care hospital in Karaikal, South India.