Isokinetic Total Work and Mitochondrial Oxidative Capacity Are Correlated in Appraising Hamstrings Endurance Performance of Young, Healthy, and Highly Active Adults.

Purpose: To assess the association between skeletal-muscle endurance performance and mitochondrial oxidative capacity of the hamstrings as respectively measured by biomechanical and physiological standards.

Methods: Nineteen (12 men and 7 women) healthy, young, recreationally active participants enrolled in our study. Participant characteristics comprised a mean and SD age of 21.

A Process Evaluation of the UK Randomised Trial Evaluating 'iSupport', an Online e-Health Intervention for Adult Carers of People Living with Dementia.

Supporting dementia carers is a global priority. As a Randomised Controlled Trial (RCT) (n = 352) of the Word Health Organization recommended, an internationally disseminated 'iSupport' e-health intervention was conducted, revealing no measurable benefits to the wellbeing of adult dementia carers. This process evaluation contributes original insights of the trial outcomes.

Capillary electrophoresis mis-anchoring in a case of Hb hope with HbE.

Background: Capillary electrophoresis is a widely used method for hemoglobin (Hb) fraction separation and relative quantitation, where pre-defined Hb peaks (typically HbA and HbA2) act as reference points to "anchor" the electropherogram and define migration zones. In cases lacking HbA or involving variants with migration patterns similar to HbA or HbA2, mis-anchoring can occur-leading to incorrect zoning of Hb variants. This presents a diagnostic challenge, where follow-up investigations, often including molecular testing, are required to establish an accurate diagnosis.

A randomized controlled trial testing couple HOPES: An online, self-help couples' intervention for posttraumatic stress disorder.

Objective: This article presents a randomized waitlist-controlled trial testing Couple HOPES, a coach-guided, online intervention for couples wherein one member had posttraumatic stress disorder (PTSD) symptoms. Aims involved examining whether Couple HOPES resulted in greater improvements in PTSD symptoms, relationship satisfaction, and secondary outcomes compared to a waitlist, whether outcomes were maintained over a 3-month follow-up, and whether outcomes differed if PTSD was COVID-19-related.

Method: Sixty-seven couples were recruited, where one partner met criteria for likely PTSD and was either a military member, veteran, first responder, health care worker, and/or whose PTSD symptoms were related to COVID.

Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium.

Several regulatory agencies have developed threshold-based drinking water guidelines for hexavalent chromium [Cr(VI)] protective of nonneoplastic and neoplastic lesions in rodents using small intestine tumor data in mice. However, in 2024 the U.S.