Prenatal evaluation, diagnosis and management of fetal corpus callosal abnormalities: international Delphi consensus.

Objective: The corpus callosum (CC) is an interhemispheric structure that facilitates communication between the two cerebral hemispheres. Anomalies of the CC are frequent and associated with a wide spectrum of altered neurodevelopmental outcomes. However, variability in diagnostic criteria and the lack of standardized management strategies create challenges for clinicians and anxiety for expectant parents.

An Unusual Mainly Skeletal Prenatal Presentation of Cornelia de Lange Syndrome Due To a Novel Variant in NIPBL.

CNLS is a multisystemic malformative syndrome caused by variants in genes of the cohesin complex, with the most common form due to variants in NIPBL. Phenotype is variable, but facial dysmorphisms and skeletal anomalies represent the most common expressions of the syndrome. In this report, we describe de novo c.

Transvaginal ultrasound assessment of corpus callosal length in the fetus: multicenter cross-sectional study.

Objective: To produce reference ranges and Z-scores for corpus callosal (CC) length in the fetus, based on transvaginal three-dimensional (3D) ultrasound imaging.

Methods: This was a cross-sectional multicenter retrospective study based on 3D volume dataset acquisitions of the fetal CC between the 15 and 37 weeks of gestation. Only volume datasets acquired transvaginally through the anterior fontanelle were selected.