Real-time monitoring of canopy chlorophyll content is crucial for understanding crop growth and guiding precision agricultural management. The SPAD chlorophyll meter is a valuable tool for assessing nitrogen status in maize (Zea mays L.), a key cereal crop used for food, feed, and biofuels.
View Article and Find Full Text PDFIntroduction: Acute appendicitis is a common pediatric surgical emergency requiring timely intervention. Conventional three-port laparoscopic appendectomy (CLA) is widely used, offering reduced postoperative pain, faster recovery, and lower wound infection rates. The transumbilical laparoscopic-assisted appendectomy (TULAA) technique, a single-incision approach, promises improved cosmetic outcomes, shorter operative time, and reduced morbidity.
View Article and Find Full Text PDFEur J Med Chem
March 2025
MRE11 nuclease is a central player in signaling and processing DNA damage, and in resolving stalled replication forks. Here, we describe the identification and characterization of new MRE11 inhibitors MU147 and MU1409. Both compounds inhibit MRE11 nuclease more specifically and effectively than the relatively weak state-of-the-art inhibitor mirin.
View Article and Find Full Text PDFCastleman's disease (CD) is characterised by benign lymphoepithelial proliferation and is a peculiar form of angiofollicular lymph node hyperplasia rather than a neoplasm or a hamartoma. CD is broadly classified as unicentric CD (UCD) and multicentric CD. In the unicentric variant, patients have localised disease affecting only a single lymph node or a group of adjacent nodes in a single region, which clinically presents as an enlarging mass without any other significant symptoms.
View Article and Find Full Text PDFA highly stereoselective total synthesis of polyrhacitide A, a polyketide natural product, has been accomplished by means of Prins cyclisation. The key precursor i.e.
View Article and Find Full Text PDF