Traumatic Brain Injury Severity Measured by Clinical, Radiographical, and Blood Biomarker Measures Is Associated with Non-Neurological Organ Dysfunction: A Secondary Analysis of ProTECT III and Bio-ProTECT.

Non-neurological organ dysfunction (NNOD) is a prevalent complication and contributes to poor outcome after traumatic brain injury (TBI). Contributing factors to NNOD may include initial TBI severity, but this relationship has not been rigorously studied. The objectives of this study were to describe the frequency and timing of NNOD after TBI, evaluate the association between NNOD and outcome (mortality and Glasgow Outcome Score-Extended [GOSE] at 6 months post-injury), and examine the relationship between multimodal markers of initial TBI severity and NNOD.

GHz-Speed Wavefront Shaping Metasurface Modulators Enabled by Resonant Electro-Optic Nanoantennas.

Electrically tunable metasurfaces that control the amplitude and phase of light through biasing of nanoscale antennas present a route to compact modulator devices. However, most platforms face limitations in bandwidth, optical efficiency, and tuning response. Electro-optically tunable metasurfaces achieving both GHz amplitude modulation and transmissive wavefront shaping in the telecom range are presented.

Multidisciplinary multivisceral resections involving the upper digestive tract: a United Kingdom tertiary cancer centre experience.

Purpose: Multivisceral surgical resections (MVR) are highly specialised procedures involving multidisciplinary surgical teams. MVR can be performed to achieve a complete oncological resection of tumours or to achieve cytoreductive surgery. The aim of the study is to evaluate the peri-operative outcomes of patients undergoing oncological multivisceral or multi-tissue resection which involved concomitant resection of the upper digestive tract/organs (oesophagogastric and hepatopancreatic-biliary).

Modeling nonlinear oscillator networks using physics-informed hybrid reservoir computing.

Surrogate modeling of non-linear oscillator networks remains challenging due to discrepancies between simplified analytical models and real-world complexity. To bridge this gap, we investigate hybrid reservoir computing, combining reservoir computing with "expert" analytical models. Simulating the absence of an exact model, we first test the surrogate models with parameter errors in their expert model.

Enterovirus C recombination groups: RNA sequence similarity and the viral polymerase underpin sexual replication mechanisms.

Unlabelled: Enteroviruses frequently recombine with one another in nature; however, it is unclear how viral replication machinery can distinguish between related and unrelated partners during recombination. We hypothesize that viral RNA recombination involves two parental RNA templates, nascent RNA products, and their dynamic interactions with the viral polymerase-a sexual replication strategy. When nascent RNA products move from one parental RNA template to another, RNA sequence similarity may be an important factor underpinning the mechanism and efficiency of recombination.