DIGITAL 3D "HEADS-UP" LASIK SURGERY: FEASIBILITY, SURGICAL DURATION, COMPLICATION RATES AND COMPARISON WITH A CONVENTIONAL MICROSCOPE.

Purpose: This study aims to compare LASIK surgery using the NGENUITY 3D visualization system (Alcon) with surgery conducted using the conventional microscope of the Wavelight EX500 excimer laser (Alcon), by an experienced surgeon (>500 procedures) and a young surgeon (<50 procedures).

Settings: Single centre study at the Rothschild Foundation, Paris, France.

Design: Prospective cross-sectional study.

Corneal intrastromal silicone injection in severe corneal decompensation as a last resort for pain management: A case series.

Purpose: To describe a surgical approach to treating painful bullous keratopathy using an intracorneal silicone bubble in patients with poor visual potential.

Methods: Two eyes of two patients with painful bullous keratopathy are presented in this paper. The surgical technique consists of two steps.

Validation of a new Implantable Collamer Lens sizing algorithm based on the Anterion swept source OCT images.

Purpose: To evaluate the performance of a novel deep learning-based Implantable Collamer Lens (ICL) sizing model that uses raw Swept-Source OCT images as input.

Setting: Multicentric European study.

Design: Retrospective external validation study.

A two-step formula constant optimization strategy for minimal standard deviation and zero mean prediction error in IOL power calculation.

Purpose: To investigate the precision and accuracy performance of a two-step approach for optimizing lens formula constants (FC) with a refractive offset correction (RO) as a second tuning parameter.

Methods: Using IOLMaster 700 biometric data from 4 datasets (886/613/821/467 eyes treated with the Hoya Vivinex/Johnson&Johnson ZCB00/Alcon SA60AT/Bausch&Lomb MX60 lens), and the power of the implanted lens and postoperative spherical equivalent refraction, FC and RO were optimized for SRKT, Hoffer Q, Holladay 1, and Haigis formulae using an iterative nonlinear optimization for RMSPE and sequentially according to Gatinel, optimizing first FC for standard deviation prediction error (SDPE) and then RO by the resulting mean prediction error.

Results: The simple two-step approach yielded comparable results for the FC and RO for all four formulae and datasets under test.

Monoclonal gammopathy presenting with paraproteinemic keratopathy documented with anterior segment OCT: a case report.

Background: Paraproteinemic keratopathy (PPK) is a rare ocular manifestation of monoclonal gammopathies such as monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM). Although these hematologic conditions are relatively common in older adults, their ocular presentations remain underrecognized or misdiagnosed. We report a case of PPK where anterior segment optical coherence tomography (AS-OCT) revealed a unique mixed-layer deposition pattern, contributing new imaging insights to the clinical spectrum of PPK and underscoring the importance of ophthalmic findings in prompting systemic evaluation.