The Potential Impact of Ending the Ryan White HIV/AIDS Program on HIV Incidence: A Simulation Study in 31 U.S. Cities.

Background: With antiretroviral therapy, people with HIV can live a normal lifespan and not transmit HIV. The Ryan White HIV/AIDS Program provides care for over half of people with HIV in the United States.

Objective: To estimate how many HIV infections could result from cessation of Ryan White services or interruptions lasting 18 to 42 months.

Mid-day photomixotrophy by spp. and implications for the C content of hot spring cyanobacterial mats.

Unlabelled: Microbial mats inhabiting extreme environments have been studied as modern analogs of stromatolites. Mats in Octopus Spring and Mushroom Spring, Yellowstone National Park, are predominated by unicellular photoautotrophic cyanobacteria ( spp.), which are thought to cross-feed filamentous photoheterotrophic bacteria (mainly spp.

A reconsidered diagnosis in an unresolving myocarditis-a case report.

Background: Myocarditis typically presents with chest pain, a raised troponin and is associated with late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR). However, non-resolution of symptoms despite treatment should raise cause for concern that an alternative diagnosis may be present.

Case Summary: A 17-year-old gentleman with a background history of developmental delay, gastrointestinal motility issues, retractile testes, and patellar dislocation presented to our emergency department with chest pain.

Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA.

Background: Non-invasive urine tests for bladder cancer (BC) could reduce dependence on flexible cystoscopy for diagnosis and surveillance. Most recent developments in urine testing are based on targeted detection of genomic and/or epigenomic markers. We hypothesised that long-read whole-genome sequencing of urinary DNA with direct methylation profiling may allow accurate BC detection and insights into disease biology.

Evaluation of a learning collaborative on team-based care: qualitative analysis of coaching calls using normalisation process theory.

Evaluation of learning collaboratives (LC) needs to account for not just outcomes and context, but also the mechanisms participating teams use to implement and normalise new practices. Normalisation process theory (NPT) mechanisms-, , and -were used to do a constant comparison coding of transcripts of weekly calls between team coaches and mentors during a 9-month LC to implement team-based primary care in 13 health centres. Both the positive and negative (eg, lack of ) use of normalising mechanisms, as well as when they occurred over time, were noted.