Randomized Clinical Trial on Caries Prevention of Silver Diamine Fluoride.

This 30-mo double-blind randomized clinical superiority trial aimed to assess the effectiveness of semiannual application of 38% silver diamine fluoride (SDF) solution in preventing early childhood caries in primary upper anterior teeth. The active comparator was 5% sodium fluoride varnish (FV). The primary outcome was the mean number of new carious tooth surfaces per child at the 30-mo follow-up.

Topical Fluoride in Preventing Occlusal Caries in Children in a Fluoridated Area: A Randomized Clinical Trial.

This study aimed to investigate the effectiveness of the semi-annual application of 38% silver diamine fluoride (SDF) and that of 5% sodium fluoride (NaF) varnish in preventing occlusal cavitated caries in the primary molars of preschool children over a 30-mo period. This was a parallel 3-arm, double-blind, randomized controlled trial. Generally healthy children around 3 y old were randomly allocated to 1 of the 3 study groups: group 1: 38% SDF solution; group 2: 5% NaF varnish; and group 3: tonic water (placebo).

A Randomized Controlled Trial of Silver Diamine Fluoride Application Time.

Clinicians have recommended, with no scientific evidence, increasing the application times of 38% silver diamine fluoride (SDF) to foster caries arrest. The current study determined the rate of carious lesion activity in response to topical 38% SDF with increasing treatment application time. A 6-mo, stratified-randomized, double-blind, active-controlled, parallel-group trial compared 9 treatment arms.

Dental Caries Status of Children and Adolescents in West Africa-A Literature Review.

Dental caries is one of the most prevalent oral diseases worldwide, including in Africa. The aim of this article was to provide a comprehensive review of dental caries status of children and adolescents living in the West African region. Articles that fulfilled the study selection criteria were identified through systematic search in electronic databases (EMBASE and MEDLINE).