Diabetes mellitus and hypertension care in Bidur Municipality, Nuwakot District, Nepal: A cross-sectional study.

Chronic diseases, such as diabetes mellitus (DM) and hypertension (HTN), are growing public health concerns globally, with notably low management rates in low- and middle-income countries. This study aimed to assess the care-related outcomes of DM and HTN in Bidur Municipality, Nepal. This cross-sectional study was conducted in Bidur Municipality in Nuwakot District of Nepal.

Computational investigation of mutations in PfCRT and PfDHFR proteins for emerging resistance of Plasmodium falciparum to antimalarial drugs.

The emergence of multidrug resistance in Plasmodium falciparum poses a serious threat to antimalarial treatment, particularly with growing resistance to artemisinin-based combination therapies (ACTs) and partner drugs like piperaquine. Mutations in key proteins, such as PfCRT (P. falciparum chloroquine resistance transporter) and PfDHFR (P.

The XBB.1.5 COVID-19 vaccine elicits a durable antibody response to ancestral and XBB.1.5 SARS-CoV-2 spike proteins.

The rapid emergence of divergent SARS-CoV-2 variants led to a 2023-2024 update of the COVID-19 mRNA vaccine to a monovalent version containing the XBB.1.5 SARS-CoV-2 spike antigen.

Circulating MicroRNAs as diagnostic indicators in tuberculous Meningitis-A case -control study in North Indian population.

Purpose: Tuberculous meningitis (TBM), a severe and often fatal form of tuberculosis, showing high mortality and long-term neurological sequelae. Recent evidence suggests that microRNAs play a crucial role in TBM pathogenesis and may serve as potential biomarkers for diagnosis and disease progression.

Methods: Eight TBM patients and three healthy controls were recruited.

Arthroscopic Osteochondral Autograft Transplantation (OAT) in Patients with Focal Osteochondral/Chondral Lesions of the Knee Mid-Term Clinical Outcome.

Introduction: Articular cartilage has limited healing potential as it is a hypocellular and avascular structure, hence it is to manage articular cartilage defects. The arthroscopic osteochondral autograft transplantation procedure is minimally invasive and cosmetically acceptable procedure to manage cartilage defects.

Materials And Methods: This is a prospective study extending from 2018 to 2023 done at Sports Injury Center, New Delhi involving 36 patients with focal full-thickness chondral/osteochondral defect, age <45 were included.