Background: Hypertension remains a critical public health issue in Germany, affecting millions of individuals. Mobile health applications (mHealth apps) offer promising solutions for improving patient outcomes and adherence in hypertension management. Despite their advantages in healthcare, the adoption of mHealth apps by general practitioners (GPs) in Germany remains limited to date.
View Article and Find Full Text PDFBackground: Arterial hypertension is one of the leading causes of premature death worldwide. In the care of patients with hypertension, digital tools - such as apps or wearables - can potentially help in prevention to facilitate lifestyle changes or to improve blood pressure control. In hypertension care in Germany, digital applications are only sporadically used by patients and recommended by physicians.
View Article and Find Full Text PDFObjectives: Asynchronous telemedicine-based second opinions, using a purely document-based and written procedure, offer an opportunity to support patients in their medical decision-making, particularly those who cannot secure a timely face-to-face appointment nearby. The aim of the study is to investigate the benefits and challenges of asynchronous telemedicine in obtaining a second opinion and clarify for whom and under what conditions it is suitable.
Design: We conducted a qualitative interview study as part of a larger mixed-methods study.
Am J Physiol Heart Circ Physiol
June 2025
Thrombospondins (TSPs) are matricellular proteins involved in intimal hyperplasia (IH). We hypothesized that ) TSP-1, TSP-2, and TSP-5 are interdependent regarding their effects on vascular smooth muscle (VSMC) physiology; ) local or systemic knockout of or reduces IH, with its combination () being most effective; ) local or systemic knockout of increases IH; and ) the effects of TSPs differ between males and females. In vitro, VSMCs were transfected with siRNA against , , , or VSMC proliferation by TSP-1, TSP-2, or PDGF-BB was tested, and chemotaxis to TSP-1, TSP-2, TSP-5, or PDGF-BB was assessed.
View Article and Find Full Text PDFBackground: Mobile health (mHealth) apps provide innovative solutions for improving treatment adherence, facilitating lifestyle modifications, and optimizing blood pressure control in patients with hypertension. Despite their potential benefits, the adoption and recommendation of mHealth apps by physicians in Germany remain limited. This reluctance may be due to a lack of understanding of the factors influencing physicians' willingness to incorporate these digital tools into routine clinical practice.
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