A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis.

Background: Individuals with serum elevations of anti-cyclic citrullinated peptide (anti-CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such 'at-risk' individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.

Current Techniques in the Imaging of Gout.

Gout is a common inflammatory arthritis with well-described imaging characteristics. Radiography depicts erosive change and in advanced cases, tophus deposition near joints and in association with tendons or bursae. Computed tomography demonstrates the same features but may also use dual-energy or photon-counting techniques that allow for tissue composition analysis and the specific identification of monosodium urate deposition.

Strategies for successful integration of work from home faculty in an academic radiology department.

Academic radiology departments have added increasing numbers of entirely remote "work-from-home" or hybrid faculty. This change has presented both an opportunity to recruit and retain faculty as well as a set of challenges to maintaining the full academic mission and educational environment. In this article we describe our experience with creating a remote faculty position and the key elements that we believe made it successful.

SSR white paper: guidelines for utilization and performance of direct MR arthrography.

Objective: Direct magnetic resonance arthrography (dMRA) is often considered the most accurate imaging modality for the evaluation of intra-articular structures, but utilization and performance vary widely without consensus. The purpose of this white paper is to develop consensus recommendations on behalf of the Society of Skeletal Radiology (SSR) based on published literature and expert opinion.

Materials And Methods: The Standards and Guidelines Committee of the SSR identified guidelines for utilization and performance of dMRA as an important topic for study and invited all SSR members with expertise and interest to volunteer for the white paper panel.

Radiographic assessment of acute vs chronic vertebral compression fractures.

Purpose: Distinguishing between acute and chronic vertebral compression fractures typically requires advanced imaging techniques such as magnetic resonance imaging (MRI). Recognizing specific radiographic findings associated with fracture acuity may improve the accuracy of radiographic assessment.

Methods: Patients with compression fractures that had both radiographic and MRI studies of the lumbar spine within a 30-day time frame were retrospectively reviewed.

MR Imaging of Knee Cartilage Injury and Repair Surgeries.

Cartilage injuries are common and may predispose to early accelerated osteoarthritis. Magnetic resonance (MR) imaging is critical in the detection and characterization of acute and chronic cartilage injuries. Several surgical approaches including microfracture, osteochondral allografting, autologous osteochondral transfer system, and autologous chondrocyte implantation have been developed to treat cartilage lesions.

Mass-Like Fat at the Medial Midfoot: A Common Pseudolesion.

Fatty masses are common and may be encountered in the foot and ankle. In some cases, normal subcutaneous fat may be mistaken for a discrete mass. The aim of this study was to evaluate the common finding of prominent subcutaneous fat at the medial midfoot resembling a lipoma and to determine the prevalence of this pseudolesion by applying a series of potential size cutoff criteria.

A multicenter, double-blind, randomized controlled trial comparing magnetic resonance imaging evaluation of repaired versus unrepaired interportal capsulotomy in patients undergoing hip arthroscopy for femoroacetabular impingement.

The purpose of this study was to evaluate the magnetic resonance imaging (MRI) appearance of the hip capsule in patients with femoroacetabular impingement (FAI) undergoing hip arthroscopy with capsular repair versus non-repair. A multicenter clinical trial was performed with 31 patients (49 hips) undergoing hip arthroscopy for treatment of FAI. A small- to moderate-sized interportal capsulotomy was performed.

Postoperative Imaging in the Setting of Hip Preservation Surgery.

Osteoarthritis of the hip remains a prevalent disease condition that influences ever-changing treatment options. Procedures performed to correct anatomic variations, and, in turn, prevent or slow the progression of osteoarthritis, are aptly referred to as types of hip preservation surgery (HPS). Conditions that predispose individuals to femoroacetabular impingement (FAI), including pincer- and cam-type morphology, and hip dysplasia are specifically targeted in HPS.

Introduction of a virtual workstation into radiology medical student education.

OBJECTIVE. This article describes the creation of a virtual workstation for use by medical students and implementation of that workstation in the reading room. CONCLUSION.

Video: Ultrasound-guided intervention at the posterior hip.

Objective: The purpose of this video article is to demonstrate sonographic anatomy at the posterior hip and to describe a number of diagnostic and therapeutic interventions that may be performed at this location with sonographic guidance. Injection techniques at the piriformis muscle, ischial bursa, hamstring origin, and ischiofemoral space are described and demonstrated.

Conclusion: Ultrasound is well adapted to the evaluation and treatment of conditions encountered at the posterior hip.

Prevalence of abnormal hip findings in asymptomatic participants: a prospective, blinded study.

Background: The prevalence of abnormal magnetic resonance imaging (MRI) findings in an asymptomatic population has yet to be determined.

Purpose: The purpose of this study was to assess a cohort of asymptomatic people to determine the prevalence of hip lesions.

Study Design: Cross-sectional study; Level of evidence, 3.

Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?

Objective: To evaluate the presence of pulmonary abnormalities in rheumatoid arthritis (RA)-related autoantibody-positive subjects without inflammatory arthritis.

Methods: Forty-two subjects who did not have inflammatory arthritis but were positive for anti-cyclic citrullinated peptide antibodies and/or ≥2 rheumatoid factor isotypes (a profile that is 96% specific for RA), 15 autoantibody-negative controls, and 12 patients with established seropositive early RA (<1-year duration) underwent spirometry and high-resolution computed tomography (HRCT) lung imaging.

Results: The median age of autoantibody-positive subjects was 54 years, 52% were female, and 38% were ever-smokers; these characteristics were not significantly different from those of autoantibody-negative control subjects.

Morphologic imaging of articular cartilage.

Magnetic resonance (MR) imaging plays an integral role in the assessment of articular cartilage. This article discusses the role of MR imaging in the evaluation of articular cartilage, the appearance of cartilage lesions on MR imaging, and the currently available MR imaging techniques for evaluating cartilage morphology. A limitation of currently available sequences is their inability to consistently detect superficial degenerative and posttraumatic cartilage lesions that may progress to more advanced osteoarthritis.