Primary lung adenocarcinoma is a rare but critical diagnosis in young adults, often presenting with atypical symptoms. We report the case of a 29-year-old male with no significant medical history who initially presented with deep vein thrombosis (DVT) and recurrent pulmonary emboli (PE) despite appropriate anticoagulation. Further workup ultimately revealed metastatic lung adenocarcinoma, diagnosed post-mortem.
View Article and Find Full Text PDFDrug-induced liver injury (DILI) is a leading cause of acute liver failure in the U.S., though allopurinol and colchicine have not been widely associated with fulminant hepatic failure.
View Article and Find Full Text PDFIntroduction: Rickets is a disorder of defective bone mineralization resulting in skeletal deformities, growth retardation, and increased risk of fractures. Nutritional rickets, once a historical disease, has reemerged in select pediatric populations despite modern food fortification efforts. Many of the most common food allergens - dairy, eggs, and fish - are primary dietary sources of vitamin D, which presents a unique risk factor for development of rickets.
View Article and Find Full Text PDFWe report a 62-year-old, Hispanic male who presented to a rural medical provider who noted dark nail discoloration to the left thumb. Several weeks later, he presented to a rural emergency department with left thumb subungual hematoma and paronychia attributed to recent trauma. After evacuation and oral antibiotics, the provider discussed the prospect of melanoma given presence of longitudinal melanonychia and positive Hutchinson's sign.
View Article and Find Full Text PDFWe report an 83-year-old woman who presented to her primary care provider with pain and swelling of her left thumb distal phalanx for 1 week. Initial imaging was benign. The patient underwent treatment for presumed soft tissue infection with 2 separate oral antibiotic courses.
View Article and Find Full Text PDFA Caucasian male in his 60s presented with acute onset of dizziness, dysarthria, and gait ataxia. Upon extensive workup, positive findings were cerebrospinal fluid (CSF) showing lymphocytic pleocytosis with oligoclonal bands, positive celiac disease autoantibodies in blood, a duodenal biopsy indicating lymphocytic infiltration, and positive anti-mGluR1 antibody titers in CSF. The patient was started on a strict gluten-free diet and intravenous immunoglobulin therapy for 5 days and showed mild consecutive improvements each day of treatment.
View Article and Find Full Text PDFObjective: To present a single-center prospective study of 126 consecutively treated patients who underwent endovascular repair of a thoracoabdominal aortic aneurysm with the physician-modified, nonanatomic-based Unitary Manifold (UM) device.
Methods: Data were collected from 126 consecutive all-comer patients treated with the physician-modified, nonanatomic-based UM from 2015 to 2023. Treatment was performed at a single center by a single physician under a Physician Sponsored Investigation Exemption G140207.
Introduction: Many orthopedic providers currently treat chronic spondylolysis as self-limited fractures. While the condition has previously been associated with back pain in pediatrics, there has been little attention on the risk of neurologic harm. Electromyography (EMG) is a common study used to evaluate nerve injury, but it has not been previously reported for testing pediatric patients with stress fractures.
View Article and Find Full Text PDF