Publications by authors named "Clement Servoz"

Background: Coronary sinus (CS) Reducer implantation shows favorable results in alleviating angina symptoms in patients with obstructive coronary artery disease (CAD) with non-revascularizable lesions. Whether CS Reducer is effective also in patients without obstructive epicardial CAD remains unsettled.

Aims: We sought to assess the potential benefits of the CS narrowing in patients without obstructive presenting with refractory angina.

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Background: Data concerning the long-term durability of transcatheter aortic valves (TAVs) in patients with bicuspid aortic stenosis (AS) are lacking.

Aims: The study aims to report data on long-term valve durability following transcatheter aortic valve replacement (TAVR) in bicuspid AS.

Methods: This multicentre registry included patients who underwent TAVR for bicuspid AS with at least 2-year echocardiographic follow-up.

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Background: Despite a frequently favorable evolution during the initial phase, acute myocarditis (AM) remains associated with heart failure and ventricular arrhythmia. There are no large prospective databases to provide robust results.

Objectives: The aim of this study was to describe baseline characteristics, real-life management, in-hospital outcomes, and determinants of prognosis in a large cohort of patients with AM admitted to cardiology, with a comparison of patients with and without initial severity criteria.

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Article Synopsis
  • Acute myocarditis is a serious condition that often presents with chest pain and elevated troponin, usually in young, healthy adults, and is a leading cause of sudden cardiac death despite having normal coronary arteries.
  • The study aimed to analyze the characteristics, management, and outcomes of acute myocarditis over an extended period, focusing on survival rates and treatment approaches.
  • The MyocarditIRM cohort involves 803 patients across 49 centers in France, utilizing cardiac magnetic resonance for diagnosis, and aims to provide a comprehensive understanding of acute myocarditis through long-term follow-up linked to the national health database.
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We report the case of a 79-year-old male patient who benefited from the implantation of a coronary sinus reducer (CSR) (Reducer; Neovasc, Inc.) in the management of typical angina with mild exertion with optimal medical treatment.

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To date, the best approach to coronary bifurcation lesion remains unsettled, and the parameters to guide side branch ballooning or stenting are not yet defined. This study aimed to compare the survival outcomes after provisional stenting with versus without side branch intervention. A cohort was conducted on 132 patients who underwent coronary angiography at Toulouse University Hospital for ST-segment elevation myocardial infarction with large culprit nonleft main coronary bifurcation lesion.

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Article Synopsis
  • The study examined patients with prosthetic valve endocarditis (PVE) after transcatheter aortic valve implantation (TAVI), focusing on those with absent vs. evident echocardiographic signs of infective endocarditis (IE).
  • Among 578 patients, 15.1% had no echocardiographic signs, mostly treated via transfemoral access and showing more complications compared to those with evident signs.
  • Patients with absent imaging had higher rates of infections from Staphylococcus aureus and enterococci but similar in-hospital and one-year mortality risks, indicating they still represent a high-risk group for IE despite negative imaging.
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Background: Outcomes after transcatheter aortic valve replacement (TAVR) and infectious diseases may vary according to sex.

Methods: This multicentre study aimed to determine the sex differences in clinical characteristics, management, and outcomes of infective endocarditis (IE) after TAVR. A total of 579 patients (217 women, 37.

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Scarce data exist on mitral valve (MV) infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI). This multicenter study included a total of 579 patients with a diagnosis of definite IE after TAVI from the IE after TAVI International Registry and aimed to evaluate the incidence, characteristics, management, and outcomes of MV-IE after TAVI. A total of 86 patients (14.

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Background: Scarce data exist about early infective endocarditis (IE) after trans-catheter aortic valve replacement (TAVR).

Objective: The objective was to evaluate the characteristics, management, and outcomes of very early (VE) IE (≤ 30 days) after TAVR.

Methods: This multicenter study included a total of 579 patients from the Infectious Endocarditis after TAVR International Registry who had the diagnosis of definite IE following TAVR.

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Background: The optimal treatment of patients developing infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) is uncertain.

Objectives: The goal of this study was to investigate the clinical characteristics and outcomes of patients with TAVI-IE treated with cardiac surgery and antibiotics (IE-CS) compared with patients treated with antibiotics alone (IE-AB).

Methods: Crude and inverse probability of treatment weighting analyses were applied for the treatment effect of cardiac surgery vs medical therapy on 1-year all-cause mortality in patients with definite TAVI-IE.

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Background: Infective endocarditis (IE) following transcatheter aortic valve replacement (TAVR) has been associated with a dismal prognosis. However, scarce data exist on IE perivalvular extension (PEE) in such patients.

Methods: This multicenter study included 579 patients who had the diagnosis of definite IE at a median of 171 (53-421) days following TAVR.

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During stent positioning after predilating with a non-compliant balloon, we observed major motion of our device in the left main coronary artery. Under those conditions, accurate stent placement was uncertain. To remedy this situation, we decided to perform a rapid direct wire pacing with a good final angiographic result.

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Background: Staphylococcus aureus (SA) has been extensively studied as causative microorganism of surgical prosthetic-valve infective endocarditis (IE). However, scarce evidence exists on SA IE after transcatheter aortic valve replacement (TAVR).

Methods: Data were obtained from the Infectious Endocarditis After TAVR International Registry, including patients with definite IE after TAVR from 59 centres in 11 countries.

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Background: Stroke is one of the most common and potentially disabling complications of infective endocarditis (IE). However, scarce data exist about stroke complicating IE after transcatheter aortic valve replacement (TAVR).

Objectives: The purpose of this study was to determine the incidence, risk factors, clinical characteristics, management, and outcomes of patients with definite IE after TAVR complicated by stroke during index IE hospitalization.

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Article Synopsis
  • The study observed 552 patients with infective endocarditis (IE) after transcatheter aortic valve replacement (TAVR) to analyze changes over time between pre-2014 and post-2014 cohorts.
  • Overall IE rates were stable, but early IE occurrences dropped significantly in the contemporary cohort, with enterococci being the most common bacteria identified.
  • In-hospital and one-year mortality rates showed a gradual decline, alongside lower instances of acute kidney injury, although surgical intervention rates remained consistently low across both cohorts.
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Background: Appropriate information about the benefits and risks of invasive procedures is crucial, but limited data is available in this field. The aim of this study was to evaluate the incremental value of a short video about coronary angiography compared with standard information, in terms of patient understanding, satisfaction and anxiety.

Methods: This prospective multicenter study included patients admitted for scheduled coronary angiography, who were randomized to receive either standard information or video information by watching a three-dimensional educational video.

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