Publications by authors named "Clement Devautour"
Purpose: In-ICU and in-hospital deaths in critically ill patients are often subsequent to decisions of limitations of life-sustaining therapies (LLST). While septic shock remains associated with high mortality and reduced quality of life in survivors, we addressed the frequency, the decision-making process, the determinants and the attributable mortality of LLST decisions in this setting.
Materials And Methods: A retrospective (2008-2021) single-center study including consecutive adult patients with septic shock.
Severe bleeding events among critically ill patients with haematological malignancies.
Ann Intensive Care
October 2024
Article Synopsis
- Severe bleeding events are a common complication for critically ill patients with hematological cancers; a study analyzed data from 1012 such patients admitted to the ICU over 12 years.
- Out of these patients, 10.8% experienced severe bleeding events after 3 days in the ICU, primarily from the gastrointestinal tract, which led to longer hospital stays and higher mortality rates.
- Key predictors for these bleeding events included having chronic kidney disease and entering the ICU with an existing primary bleeding problem.
Article Synopsis
- This study aims to evaluate the long-term outcomes of ICU survivors with acute myeloid leukemia (AML) or aggressive B-cell non-Hodgkin lymphoma (B-NHL), focusing on their ability to resume optimal cancer treatment after ICU discharge.
- The research included a retrospective analysis of 366 patients, finding that 170 survivors were left with substantial treatment modifications; with 42% requiring changes due to factors such as age, hyperbilirubinemia, and therapeutic limitations.
- The one-year survival rate after ICU discharge was 59.5%, highlighting the need for careful management of cancer treatments in this vulnerable patient population to improve outcomes.