Publications by authors named "Chun-Ming Yin"
Self-Nanoemulsifying Drug Delivery System of Genkwanin: A Novel Approach for Anti-Colitis-Associated Colorectal Cancer.
Drug Des Devel Ther
October 2021
Article Synopsis
- The study focused on creating an optimized self-nanoemulsifying drug delivery system (SNEDDS) for Genkwanin (GKA) to improve its solubility, intestinal absorption, and effectiveness against colitis-associated colorectal cancer (CAC).
- The formulation was developed by testing various oils and surfactants, leading to a successful mixture that enhanced GKA's properties, making it more bioavailable and effective in a mouse model of CAC.
- The optimized GKA-SNEDDS resulted in a remarkable 353.28% increase in bioavailability compared to regular GKA and demonstrated significant improvements in health metrics and inflammation reduction in the experimental model of cancer.
In the present study we investigated the effects of different durations of using high-heeled shoes on plantar pressure and gait. A questionnaire survey and dynamic plantar pressure measurements were performed in 20 control females and 117 females who had worn high-heeled shoes for a long time. According to the duration of using high-heeled shoes (as specified in the questionnaire), subjects were divided into a control group and five groups with different durations of use (i.
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