High-Flux Microporous Layers with Bimodal Pore Structures for Proton Exchange Membrane Fuel Cells.

Proton exchange membrane fuel cells (PEMFCs) are critical for heavy-duty transportation due to their high efficiency and environmental benefits. However, achieving optimal water management and gas transport in the microporous layer (MPL) remains a challenge to improving its performance. In this paper, a high-flux MPL is presented, which was prepared using pure carbon nanotubes (CNT) by adding a nonionic surfactant to improve the dispersion of hydrophobic CNT.

Synthesis and anticancer evaluation of novel flavonoid-based amide derivatives as regulators of the PI3K/AKT signal pathway for TNBC treatment.

Aberrant activation of the PI3K/AKT pathway is considered in many malignant tumors and plays a crucial role in mediating malignancy progression, metastasis, and chemoresistance. Consequently, development of PI3K/AKT pathway targeted drugs is currently an attractive research field for tumor treatment. In this study, twenty-six flavonoid-based amide derivatives were synthesized and evaluated for their antiproliferation effects against seven cancer cell lines, including MDA-MB-231, MCF-7, HCC1937, A549, HepG2, GTL-16 and HeLa.