Publications by authors named "Christophe Blachetot"
Front Immunol
August 2017
Article Synopsis
- Interleukin 23 (IL23) is a cytokine that plays a crucial role in immune responses and is linked to chronic inflammation and autoimmune diseases.
- Researchers have developed nanobodies (small antibody fragments) that specifically target human IL23 with high affinity, allowing them to identify different parts of the IL23 structure.
- These nanobodies were engineered to be multivalent, meaning they can bind multiple targets, leading to better effectiveness in neutralizing IL23 and showing promise for treating conditions like Crohn's disease, rheumatoid arthritis, and psoriasis.
