First-ever exploratory study on Mahali ethnomedicine, a blend of diversity and uniqueness of knowledge in utilizing local medicinal flora and fauna (southern West Bengal, India).

Ethnopharmacological Relevance: The Mahali is a marginalized ethnic group in eastern India who primarily relies on the local medicinal flora and fauna for their healthcare needs. Their extensive knowledge of medicinal species has largely gone unrecognized for centuries. The forces of modernization and cultural infiltration pose a significant risk of eroding this invaluable treasure of knowledge over time.

Au Nanoparticles, Green Synthesized by Plants of Bignoniaceae Family: Antioxidant Powerhouses with DNA Damage Mitigation Activity.

The synthesis of nanoparticles using plant extracts has become a green approach for developing modern drugs. This study focuses on synthesizing gold nanoparticles (Au NPs) using methanolic leaf (L) and bark (B) extracts from four Bignoniaceae species with a focus on their antioxidant properties. The formation of these nanoparticles was confirmed using UV-Vis spectroscopy, while their size, shape, and morphological characteristics were analyzed through multiple analytical methods.

Quantitative Ethnobotany of Medicinal Plants from Darjeeling District of West Bengal, India, along with Phytochemistry and Toxicity Study of Buch.-Ham. ex D.Don bark.

This study offers considerable information on plant wealth of therapeutic importance used traditionally by the residents of 11 villages under three subdivisions of Kurseong, Darjeeling Sadar, and Mirik in the Darjeeling District, West Bengal. For the acquisition of ethnomedicinal information, semi-structured interviews were conducted with 47 informants, of whom 11 persons were herbalists and 36 were knowledgeable persons. Free prior informed consent was obtained from each participant prior to the collection of field data.

An ethnopharmacological approach to evaluate antiparasitic and health-promoting abilities of Pueraria tuberosa (Willd.) DC. in livestock.

In eastern India, the tubers of Pueraria tuberosa (Willd.) DC. are used by the ethnic communities for its wide range of medicinal and nutritional value, especially to rejuvenate livestock health and to treat helminthiasis.

Optimization and Characterization of Phenolic Extraction Conditions and Antioxidant Activity Evaluation of L. Bark.

The presence of high levels of secondary metabolites in medicinal plants can significantly influence the progress of drug development. Here, we aimed to maximize phenolic extraction from L. stem bark using various solvents such as ethyl acetate, methanol, petroleum ether, and chloroform.

Phytochemical Profiling, Biological Activities, and In Silico Molecular Docking Studies of (L.) Mabb. & J.Wen Shoot.

(L.) Mabb. & J.

Natural Phytocompounds from Common Indian Spices for Identification of Three Potential Inhibitors of Breast Cancer: A Molecular Modelling Approach.

Breast cancer is the second most common cancer-related cause of death for women throughout the globe. In spite of some effective measures, the main concerns with traditional anti-cancer chemotherapy are its low bioavailability, physical side effects, acquired resistance of cancer cells and non-specific targeting. Now researchers have taken the initiative to establish natural product-based therapy methods and to identify viable hits for future lead optimization in the development of breast cancer medication.

A comprehensive and systematic review on potential anticancer activities of eugenol: From pre-clinical evidence to molecular mechanisms of action.

Background: Eugenol (1-allyl-4-hydroxy-3-methoxybenzene) is an important simple phenolic compound mainly derived from Syzygium aromaticum and many other plants. It is traditionally used in ayurveda and aromatherapy for the healing of many health problems. It also has significant applications in dentistry, agriculture, and flavour industry.

Inventorization and Consensus Analysis of Ethnoveterinary Medicinal Knowledge Among the Local People in Eastern India: Perception, Cultural Significance, and Resilience.

Livestock is the main backbone of the rural economy of an agriculture-based country like India. To mitigate the economic loss due to livestock's poor performance and illness, folk phytotherapy for livestock healthcare is still actively practiced in India. Literature survey revealed that the laterite region of eastern India, characterized by its cultural, ethnic, and biological diversities, as well as topographical uniqueness, lacks comprehensive information on ethnoveterinary medicinal knowledge.

Polyphenol enriched ethanolic extract of Cajanus scarabaeoides (L.) Thouars exerts potential antifilarial activity by inducing oxidative stress and programmed cell death.

Development of antifilarial drug from the natural sources is considered as one of the most efficacious, safe, and affordable approaches. In this study, we report the antifilarial activity of a leguminous plant Cajanus scarabaeoides (L.) Thouars.