Publications by authors named "Chloe Apps"

Background: Techniques to support secretion clearance for individuals with neuromuscular conditions and respiratory muscle weakness include mechanical insufflation-exsufflation and chest wall vibrations. Assessing the comparative efficacy of these techniques is challenging due to the absence of a core outcome set. We sought to describe outcomes and measurement instruments reported in studies of airway clearance techniques for individuals with neuromuscular conditions living in the community.

View Article and Find Full Text PDF

Mechanical insufflation-exsufflation (MI-E) is used to augment secretion clearance in neuromuscular patients with weakened cough strength. Cough peak flow (CPF) is a measure of cough function that is used to assess a patient's ability to clear secretions, with thresholds set that categorize cough as effective, ineffective or severely ineffective. MI-E is prescribed according to these thresholds, and CPF is used to assess titration of MI-E settings.

View Article and Find Full Text PDF

Several treatments are used in the community to improve secretion clearance for patients with neuromuscular disease (NMD). However, the optimal intervention remains unclear with further research required. We aimed to develop a core outcome set (COS) for studies investigating secretion clearance interventions used in the community by patients with NMD.

View Article and Find Full Text PDF

Introduction: Mechanical insufflation-exsufflation (MIE) is a commonly used therapy to augment secretion clearance in individuals with neuromuscular disease. There are no clear evidence-based guidelines on the settings that should be used in different diagnostic groups and how they should be titrated. We report on the settings used in the largest cohort of individuals using domiciliary MIE in the literature.

View Article and Find Full Text PDF

Objectives: Increasing numbers of patients experience a prolonged stay in intensive care. Yet existing quality improvement (QI) tools used to improve safety and standardize care are not designed for their specific needs. This may result in missed opportunities for care and contribute to worse outcomes.

View Article and Find Full Text PDF

Background: Despite substantial evidence documenting physical, psychological, and cognitive problems experienced by intensive care unit (ICU) survivors, few studies explore interventions supporting recovery after hospital discharge. Individualised recovery goal setting, the standard of care across many rehabilitation areas, is rarely used for ICU survivors. Digital health technologies may help to address current service fragmentation and gaps.

View Article and Find Full Text PDF
Article Synopsis
  • Respiratory muscle weakness can lead to ineffective coughing, increasing the risk of lower respiratory infections in patients with neuromuscular diseases; Mechanical insufflation-exsufflation (MIE) enhances cough function, but optimal techniques remain unclear.
  • The study investigates the effects of high-pressure MIE (HP-MIE) versus low-pressure MIE (LP-MIE) on lung recruitment, respiratory drive, and patient comfort in patients with respiratory muscle weakness.
  • Results show HP-MIE significantly improves cough peak flow without affecting lung recruitment or breathing comfort but may lead to upper airway closure and discomfort in patients with severe weakness.
View Article and Find Full Text PDF

Objective: To develop an expert-informed (including end users) recovery goal menu for adults recovering from critical illness applicable to the community/home setting.

Research Methodology/design: Stage 1 Item generation: iterative development of domains, sub-domains, and goals in consultation with former intensive care patients, family members and expert clinicians. Stage 2 Content validity assessment: cognitive interviews and the content validity index.

View Article and Find Full Text PDF

Adverse sequelae are common in survivors of critical illness. Physical, psychological and cognitive impairments can affect quality of life for years after the original insult. Driving is an advanced task reliant on complex physical and cognitive functioning.

View Article and Find Full Text PDF

Objectives: To inform design of quality improvement tools specific to patients with prolonged intensive care unit stay, we determined characteristics (format/content), development, implementation and outcomes of published multi-component quality improvement tools used in the intenisve care unit irrespective of length of stay.

Research Methodology: Scoping review searching electronic databases, trial registries and grey literature (January 2000 to January 2022).

Results: We screened 58,378 citations, identifying 96 studies.

View Article and Find Full Text PDF

Background And Purpose: The therapeutic benefits of prone positioning have been described over the last 50 years culminating in a systematic review supporting this management strategy for patients with severe hypoxaemic respiratory failure. Early work detailing treatment approaches for COVID-19 have advocated the use of prone positioning. Limited data exists regarding physiotherapy intervention in patients with COVID-19 owing to the recent emergence of this novel disease.

View Article and Find Full Text PDF

Background: Increasing numbers of critically ill patients experience a prolonged intensive care unit stay contributing to greater physical and psychological morbidity, strain on families and cost to health systems. Quality improvement tools such as checklists concisely articulate best practices with the aim of improving quality and safety; however, these tools have not been designed for the specific needs of patients with prolonged ICU stay. The primary objective of this review will be to determine the characteristics including format and content of multicomponent tools designed to standardise or improve ICU care.

View Article and Find Full Text PDF