Systematic review and meta-analysis: The efficacy and safety of radiofrequency ablation combined with endoscopic resection for early superficial esophageal squamous cell neoplasia.

Background: Esophageal squamous cell neoplasia (ESCN) is the sixth leading cause of cancer deaths worldwide, with patients experiencing a decrease in life expectancy. Radiofrequency ablation (RFA) and endoscopic resection (ER) have each been recommended for treatment of early superficial ESCN in the available clinical guidelines; however, the combined application of RFA and ER for treatment of early superficial ESCN remains inconclusive. We performed a meta-analysis to investigate the efficacy of RFA combined with ER in patients diagnosed with early superficial ESCN.

Implications of Serum IgG4 Levels for Pancreatobiliary Disorders and Cancer.

Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disorder presenting as mass-like lesions with obstructions. An elevated serum IgG4 level is identified in more than half of affected patients and is considered a diagnostic criterion. IgG4-RD is still easily misdiagnosed as neoplastic or infectious disease.