Radial-balanced phase transfer functions for accurate retrieval in quantitative differential phase contrast microscopy.

Quantitative differential phase contrast microscopy (qDPC) is a potent quantitative phase imaging (QPI) technique for biological applications due to its high resolution and rapid image acquisition. Traditionally, qDPC employs an asymmetric 12 axis illumination pattern and reconstructs the phase using Tikhonov regularization. Numerous endeavors have been made to enhance qDPC performance, including reducing the number of illumination patterns and refining retrieval algorithms.

Resting EEG source-level connectivity pattern to predict anhedonia improvement with agomelatine treatment in patients with major depression.

Background: Neuroimaging studies have revealed that dysfunction of reward circuitry in the brain underlies anhedonia, a core symptom of major depressive disorder (MDD) that is related to treatment outcomes. However, the relationship between the brain network at the level of neuronal oscillations and the longitudinal improvement in the severity of anhedonia is still unknown.

Methods: The study enrolled 84 unmedicated patients with MDD.

The association between anhedonia and prefrontal cortex activation in patients with major depression: a functional near-infrared spectroscopy study.

This study investigated cerebral blood flow characteristics using functional nearinfrared spectroscopy (fNIRS) in agomelatine-treated depressed patients with anhedonia. The level of anhedonia was assessed by the Snaith Hamilton Rating Scale (SHAPS) and Montgomery Åsberg Depression Rating Scale 5-item (MADRS 5-item) score. All 84 patients were evaluated on the day of the study initiation and followed at week 1, 4 and 8 after the study initiation.

Risks of mental disorders among inpatients with burn injury: A nationwide cohort study.

Objective: This investigation identified the association between burn injuries and the risk of mental disorders in patients with no documented pre-existing psychiatric comorbidities. We also examined the relationship of injury severity and the types of injury with the likelihood of receiving new diagnoses of mental disorders.

Methods: This population-based retrospective cohort study used administrative data extracted from the Taiwanese National Health Insurance Research Database (NHIRD) between 2000 and 2013.

Risks of mental disorders among intensive care unit survivors: A nationwide cohort study in Taiwan.

Objective: This study aimed to investigate the risk of mental disorders among the intensive care unit (ICU) survivors compared with the hospitalized non-ICU and non-hospitalized patients.

Method: We extracted data from the Taiwanese National Health Insurance Research Database (NHIRD) to conduct a retrospective cohort study. Multivariate Cox proportional hazard regression models were used to analyze the data.

Association between the use of antidepressants and the risk of preterm birth among pregnant women with depression: a retrospective cohort study in Taiwan.

Our study was aimed to investigate the association between the use of antidepressants and the risk of preterm birth in pregnant women who have had perinatal depression. We extracted data from the Taiwanese National Health Insurance Research Database (NHIRD) and analyzed them using multivariate Cox proportional hazard regression models. Identified from the NHIRD, we matched 1789 women aged 18-55 years who were using antidepressants during pregnancy and 1789 women who were experiencing depression but who were not using antidepressants during pregnancy for age, index date, and medical comorbidities.

Acid suppressants use and the risk of dementia: A population-based propensity score-matched cohort study.

In this population-based propensity score matched (PSM) cohort study, we aimed to investigate the risk of developing dementia with the use of acid suppressants, including proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2 antagonists). Cohorts of PPI users (n = 2,778), H2 antagonist users (n = 6,165), and non-users (n = 86,238) were selected from a dataset covering the years 2000 to 2010 in Taiwan's National Health Insurance Research Database. Patients in the three groups were PSM at a ratio of 1:1 within each comparison cohort (CC).

Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: A nationwide cohort study.

Objective: This study aimed to investigate the risk of dementia among subgroups of patients receiving concurrent antidepressant and hypnotic treatment, antidepressants alone, and hypnotics alone.

Methods: Multivariate Cox proportional hazards regression models were used to determine the effects of antidepressants and hypnotics on dementia risk after adjusting for potential confounders.

Results: Compared with the reference group, patients receiving concurrent antidepressant and hypnotic treatment had the highest adjusted hazard ratio (aHR: 2.

Increased Risk of Pain after Electroconvulsive Therapy among Depressed Patients: a Nationwide Study in Taiwan.

The risk of pain after electroconvulsive therapy (ECT) among depressed patients is still controversial. We aimed to investigate the risk of pain post-ECT among patients with depression. We investigated patients with depression, based on the data in the National Health Insurance Research Database.

Increased risk for venous thromboembolism among patients with concurrent depressive, bipolar, and schizophrenic disorders.

Objective: The study aim was to investigate the risk of venous thromboembolism (VTE) in patients with concurrent depressive, bipolar, and schizophrenic disorders.

Methods: A population-based cohort study was conducted in which information regarding psychiatric illnesses and medical comorbidities in 29,467 patients with concurrent depressive, bipolar, and schizophrenic disorders and regarding 117,868 controls were extracted. We compared the incidence of VTE between the study and control cohorts.

The Impact of Antidepressants on the Risk of Developing Obstructive Sleep Apnea in Posttraumatic Stress Disorder: A Nationwide Cohort Study in Taiwan.

Study Objectives: The association between posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) has been reported inconsistently, and the association between antidepressant use and the risk of developing OSA in patients with PTSD has not been previously studied. Therefore, we used the Longitudinal National Health Insurance Database (LHID) to investigate the impact of PTSD and antidepressant use on the risk of OSA development.

Methods: Identified from the LHID, 2,316 individuals aged ≥ 18 years with PTSD, but with no history of OSA, and 23,160 control individuals matched for age, sex, obesity and index date were enrolled between 2000 and 2015 and followed up until the end of 2015 to identify the development of OSA.

Compulsory admission is associated with an increased risk of readmission in patients with schizophrenia: a 7-year, population-based, retrospective cohort study.

Purpose: The aim of this study was to assess the risk of psychiatric readmission in patients with schizophrenia, compare it between patients prescribed compulsory admission and those consenting to voluntary admission, and determine risk factors for psychiatric readmission.

Methods: This 7-year (2007-2013), population-based, cohort study retrospectively compared data of 2038 schizophrenic inpatients who initially underwent compulsory admission (the CA group) and of 8152 matched controls with schizophrenia who initially underwent voluntary admission (the VA group).

Results: During the study period, there were 1204 and 3806 readmissions in the CA and VA groups, respectively.

Increased risk of dementia in patients with Schizophrenia: A population-based cohort study in Taiwan.

Background: The extent to which schizophrenia is associated with the risk of all-cause dementia is controversial. This study investigated the risk of dementia by type in patients with schizophrenia.

Methods: Data were collected from the Taiwanese National Health Insurance Database 2005 and analyzed using multivariate Cox proportional hazard regression models to determine the effect of schizophrenia on the dementia risk after adjusting for demographic characteristics, comorbidities, and medications.

Increased prevalence and risk of anxiety disorders in adults with tinnitus: A population-based study in Taiwan.

Objective: Tinnitus is a common disorder that may cause psychological distress and anxiety. The aim of this study was to investigate the association between anxiety disorders (ADs) and tinnitus in a large population.

Method: We conducted a cross-sectional study using the National Health Insurance Research Database in Taiwan.

Lovastatin lowers the risk of breast cancer: a population-based study using logistic regression with a random effects model.

Background: Laboratory studies have demonstrated statin-induced apoptosis of cancer cells, including breast cancer cells, and evidence is accumulating on the mechanism of statin-induced apoptosis. However, despite numerous epidemiological studies, no consensus has been reached regarding the relationship between statin use and breast cancer risk.

Methods: This retrospective case-control study enrolled 4332 breast cancer patients and 21,660 age-matched controls registered in the National Health Insurance program of Taiwan, which covers approximately 99% of the population.

One patient with Sjogren's syndrome presenting schizophrenia-like symptoms.

Comorbid depression in patients with Sjogren's syndrome has been reported frequently, while comorbid psychosis in subjects with Sjogren's syndrome has rarely been reported. Here we report a patient with Sjogren's syndrome who presented with schizophrenia-like symptoms such as persecutory delusions and auditory hallucinations in contrast to her previous psychiatric presentations, which only included depression and anxiety.

Association between sleep duration and sleep quality, and metabolic syndrome in Taiwanese police officers.

Objectives: This study's objective was to examine association between sleep duration and sleep quality, and metabolic syndrome (MetS) and its components in Taiwanese male police officers.

Material And Methods: Male police officers who underwent annual health examinations were invited to join the study and eventually a total of 796 subjects was included in it. The study subjects were divided into 5 groups according to the length (duration) of sleep: < 5, 5-5.

A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients.

Objective: Complex sleep behaviors (CSBs) are classified as "parasomnias" in the International Classifcation of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients in Taiwan.

Methods: Subjects (N = 1,220) using zolpidem or zopiclone were enrolled from the psychiatric outpatient clinics of a medical center in Taiwan over a 16-month period in 2006-2007.