Publications by authors named "Chin Sum Cheong"

Objective: This study aims to describe the incidence and risk factors of invasive fungal infection (IFI) among patients with haematological malignancies (HM) in a tertiary hospital from Malaysia.

Methods: This was a cross-sectional study in a teaching hospital involving HM patients, admitted for chemotherapy or haematopoietic stem cell transplantation (HSCT). Each admission for either chemotherapy or HSCT was considered as a separate event.

View Article and Find Full Text PDF
Article Synopsis
  • The rise of invasive fungal infections (IFIs) is notably higher in patients with hematological malignancies due to their weakened immune systems.
  • Key risk factors for developing IFIs include older age, use of immunosuppressive drugs, low white blood cell counts (neutropenia), and the presence of catheters.
  • The study highlights a lack of epidemiological data on IFIs in Asian patients and explores diagnostic and management challenges over the past decade (2011-2021).
View Article and Find Full Text PDF

Background: Peripherally inserted central venous catheters (PICC) are widely used in patients with haematological malignancies owing to the requirement for prolonged intravenous therapy. However, the growing use of PICCs has resulted in a multitude of complications such as infections and thrombosis, leading to prolonged hospitalisation periods and increased morbidity. This study aimed to determine the incidence of and factors associated with PICC-related complications in patients with haematological malignancies.

View Article and Find Full Text PDF

Background: Multiple myeloma is the third most common hematologic malignancy in Malaysia. The introduction of novel agents over the past decades has improved patient outcome and survival substantially. However, these agents incur significant economic burden, thus leading to limited use in less developed countries.

View Article and Find Full Text PDF

Cytomegalovirus (CMV) infection is one of the common complications which can lead to significant morbidity and mortality in patients after allogeneic hematopoietic stem cell transplantation (HSCT). As the seroprevalence of CMV infection in Malaysia is high, this study aims to determine the prevalence of CMV infection in patients post HSCT and to evaluate the associated risk factors. Patients who underwent allogeneic HSCT in adult ward from 2008 to 2020 at a tertiary teaching hospital in Kuala Lumpur, Malaysia were studied retrospectively.

View Article and Find Full Text PDF