Publications by authors named "Chiao-I Chang"

Article Synopsis
  • The study investigates the link between dietary patterns, glycemic control, and the risk of diabetic retinopathy (DR) in type 2 diabetes patients, focusing on how poor glucose management and oxidative stress may worsen vision loss.* -
  • It involved 136 diabetic patients with retinopathy and 466 without, analyzing their hemoglobin A1c (HbA1c) and dietary habits, finding that high HbA1c levels significantly increase the risk of DR, particularly in those with diets high in animal protein and low in vegetables.* -
  • Results suggest that poor glycemic control combined with specific dietary patterns elevates the risk of DR, highlighting the need for more extensive research to confirm these findings.*
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While the gut microbiota is known to be influenced by habitual food intake, this relationship is seldom explored in type 2 diabetes patients. This study aims to investigate the relationship between dietary patterns and gut microbial species abundance in 113 type 2 diabetes patients (mean age, 58 years; body mass index, 29.1; glycohemoglobin [HbA1c], 8.

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Although the incidence of invasive breast cancer (BC) among women in Asian is generally lower than that in Western countries, the incidence of BC has been on the rise in the past three decades in Asian countries. This hospital-based case-control study aimed to explore the relationship between dietary and metabolic factors and BC risk in pre- and post-menopausal women. We enrolled 285 patients with newly diagnosed BC at the National Taiwan University Hospital and 297 controls from the local community and hospital staff.

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Obesity has become a major public health issue which relate to numerous physical problems and highly comorbid with depression and anxiety. Recently, some studies of technology-based interventions for weight reduction emerged to overcome the barriers from time, cost and distance. Mood component and eating behavior related to obesity are less discussed so far with technology-based intervention though.

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  • - This study explored how various body composition factors affect the growth of future liver remnant volume (FLRV) in liver cancer patients preparing for surgery, analyzing data from 21 patients between May 2013 and October 2020.
  • - Researchers measured body composition via CT scans before a procedure called portal vein embolization (PVE) and tracked changes in liver volume over time, finding an average FLRV increase of 236.0 cm³, which varied based on body composition and fibrosis stage.
  • - Results showed that patients with high levels of intramuscular adipose tissue (IMAC) experienced significantly lower increases in FLRV, especially when accompanied by higher fibrosis stages, indicating an overall negative impact on liver regeneration.
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The progression of chronic kidney disease (CKD) can be directly or indirectly accelerated by a poor diet and the diet's influence on risk factors for this disease. There have been no food frequency questionnaires (FFQs) developed for the assessment of diet in patients with CKD in Taiwan. This study analyzed the validity of a short FFQ (SFFQ) with 42 items for estimating patient intake of macronutrients, fiber, phosphorus, potassium, and calcium against 3-day dietary records (3-day DRs) in Taiwanese patients with stages 3-5 CKD.

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  • Adolescents' lipid profiles can vary even among those with similar personal risk factors, highlighting the significance of the school environment in influencing these profiles.
  • A study of 2,727 Taiwanese adolescents found that factors such as low physical activity, high BMI, and sugary drink consumption negatively impacted lipid levels, while schools with more health programs helped lower LDL cholesterol.
  • The research showed that the availability of food outlets near schools significantly affected triglyceride and cholesterol levels, with a greater impact on students with higher BMIs.
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  • * Participants reported moderate compassion satisfaction (CS) and burnout (BO), with significant levels of stress, anxiety, and depression found, especially linked to high BO and compassion fatigue (CF).
  • * The study suggests a need for long-term support programs to enhance emotional well-being and adjust work conditions for hospital staff facing increased mental health risks during crises like COVID-19.
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  • The study aimed to understand how energy and protein intake affects mortality in ICU patients with different BMI categories.
  • During the research, 1693 patients were categorized by BMI, and their dietary energy and protein intake were assessed over their first 10 days in the ICU.
  • Results indicated that adequate protein intake significantly correlated with reduced mortality for patients with BMIs below 30, highlighting the need for further research on the impact of protein on better clinical outcomes.
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Background: Metabolic alterations correlate with adverse outcomes in type 2 diabetes. Dietary modification serves as an integral part in its treatment.

Objective: We examined the relationships among dietary patterns, dietary biomarkers, and metabolic indicators in type 2 diabetes ( = 871).

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Few food frequency questionnaires (FFQs) have been developed to assess diet in diabetes patients. This cross-sectional study examined the validity of a 45-item FFQ assessing the intake of macronutrients against three 24-h dietary recalls (24-HDRs) in Taiwan, and compared vegetable and fruit intakes with carotenoid biomarkers. We recruited 126 adults with type 2 diabetes who completed the FFQ and three 24-HDRs administered by a registered dietitian.

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