Analysis of the spatio-temporal distribution of Chinese professional football clubs and influential factors based on empirical evidence of clubs.

The frequent relocation of professional football clubs is a phenomenon unique to Chinese professional football, which has long attracted extensive attention from policy makers and scholars. Using data on spatial geography and competitive levels between 1994 and 2021, this research explores the spatial distribution and migration characteristics of top professional football clubs in China, in which GIS spatial analysis and exploratory spatial data analysis (ESDA) were used to analyze the influence of the regional economic, demographic, and developmental levels of the sports industry and institutional supply on the distribution and migration of clubs. The results indicate the following: (1) the overall spatial distribution of professional football clubs in China shows the pattern of "more in the east and less in the west", and the degree of club concentration gradually increases over time; (2) the migration frequency and downward migration of professional football clubs in China gradually decreased during the period of C League and CSL, and the overall situation tends to be stable; and (3) in the early stages of development of professional leagues, changes in ownership and local policy supply had a significant impact on the distribution and migration of professional clubs.

Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia.

Aims: The involvement of cyclin D1 in the proliferation of microglia, and the generation and maintenance of bone cancer pain (BCP), have not yet been clarified. We investigated the expression of microglia and cyclin D1, and the influences of cyclin D1 on pain threshold.

Methods: Female Sprague Dawley (SD) rats were used to establish a rat model of BCP, and the messenger RNA (mRNA) and protein expression of ionized calcium binding adaptor molecule 1 (IBA1) and cyclin D1 were detected by reverse transcription-polymerase chain reaction (RT-PCR) and western blot, respectively.

Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial.

Background: Propofol-induced injection pain (PIP) is a well-known problem in general anesthesia. We hypothesized that pre-treatment with remimazolam prevents PIP in patients undergoing abortion or curettage.

Materials And Methods: In this prospective, single-center, double-blinded, randomized, placebo-controlled clinical trial, adult patients aged 18 to 60 undergoing abortion or curettage were randomly assigned to three groups.

Study on Interference Connection Based on Shape Recovery of NiTiNb Shape Memory Alloy.

Interference connection is an effective method for improving the fatigue life of bolt connections. In this paper, a new method of interference connection was designed based on the shape memory effect of shape memory alloy. Using the method of numerical simulation, a finite element model was established to analyze the stress-strain rule of the bolt and the hole wall under different interference fit sizes.

Dose-dependent neurotoxicity caused by the addition of perineural dexmedetomidine to ropivacaine for continuous femoral nerve block in rabbits.

Objective: This study was designed to evaluate the neurotoxicity of dexmedetomidine combined with ropivacaine for continuous femoral nerve block in rabbits.

Methods: Thirty New Zealand rabbits were randomly divided into 5 groups of 6 rabbits each and received a continuous femoral nerve block with saline; 0.25% ropivacaine; or 1, 2, or 3 µg/mL of dexmedetomidine added to 0.

The effect of pre-process and transport strategies on survival, microbiologic, and physiologic of .

The supply chain of shellfish is complex, with animals being subjected to several stressors during the depuration, temporary keeping, and waterless-low-temp transportation processing. In this paper, the recycled water system for depuration and temporary keeping was used to realize both depuration and temporary keeping of . The samples were divided into three groups based on three different pre-process involved: samples in group 1 were depurated for 48 hr straight, whereas those in group 2 were first depured for 24 hr and then cooled for 24 hr; samples in group 3 was directly kept in a polyethylene insulation box.

Mechanical Properties Study of Fe-Mn-Si Shape Memory Alloys Welding Seam Formed by Laser Welding with Filler Powder.

To reduce the residual stress and improve the fatigue property of the laser weldment by using the stress self-accommodation characteristic of Fe-Mn-Si shape memory alloys (SMAs), a Fe15Mn5Si12Cr6Ni memory alloy welding seam was formed inside 304 stainless steel by laser welding with filler powder. The combination of the hole-drilling method and the ANSYS software was used to research the distribution law of residual stress inside the laser welding specimen. The fatigue strength of the laser welded specimens with the Fe-Mn-Si SMAs welding seam (experimental materials) and 304 stainless steel welding seam (comparative materials) was measured by cycle bending fatigue test.

Optimal central venous pressure during partial hepatectomy for hepatocellular carcinoma.

Background: Low central venous pressure (CVP) affects hemodynamic stability and tissue perfusion. This prospective study aimed to evaluate the optimal CVP during partial hepatectomy for hepatocellular carcinoma (HCC).

Methods: Ninety-seven patients who underwent partial hepatectomy for HCC had their CVP controlled at a level of 0 to 5 mmHg during hepatic parenchymal transection.

Hemodynamics and oxygen transport dynamics during hepatic resection at different central venous pressures in a pig model.

Background: Although low central venous pressure (CVP) has been used to minimize blood loss during hepatectomy, the impact of variations of CVP on the rate of blood loss and on the perfusion of end-organs has not been evaluated. This animal study aimed to evaluate the hemodynamics and oxygen transport changes during hepatic resection at different CVP levels.

Methods: Forty-eight anesthetized Bama miniature pigs were divided into 8 groups with CVP during hepatic resection controlled at 0 to <1, 1 to <2, 2 to <3, 3 to <4, 4 to <5, 5 to <6, 6 to <7, and 7 to <8 cmH2O.