White matter hyperintensities in cholinergic pathways may predict poorer responsiveness to acetylcholinesterase inhibitor treatment for Alzheimer's disease.

Background: Acetylcholinesterase inhibitor (AChEI) drug regimens are the mainstay treatment options for patients with Alzheimer's disease (AD). Herein, We examined the association between clinical response to AChEI and white matter hyperintensities on magnetic resonance imaging (MRI) scan at baseline.

Methods: Between 2020 and 2021, we recruited 101 individuals with a clinical diagnosis of probable AD.

White matter hyperintensities in cholinergic pathways are associated with dementia severity in e4 carriers but not in non-carriers.

Background And Objectives: Among individuals with Alzheimer's disease (AD), e4 carriers with increased white matter hyperintensities (WMHs) may selectively be at increased risk of cognitive impairment. Given that the cholinergic system plays a crucial role in cognitive impairment, this study aimed to identify how status modulates the associations between dementia severity and white matter hyperintensities in cholinergic pathways.

Methods: From 2018 to 2022, we recruited participants ( e4 carriers, = 49; non-carriers, = 117) from the memory clinic of Cardinal Tien Hospital, Taipei, Taiwan.

Protein supplementation enhances cerebral oxygenation during exercise in elite basketball players.

Objective: The aim of the present study was to examine cerebral oxygenation during high-intensity exercise in elite basketball players who consumed supplements with different whey protein contents after a short postexercise recovery to determine whether changing whey protein content in carbohydrate-based supplementation influences cerebral hemodynamic response when the supplement was consumed during a 2-h recovery after a 1-h exercise challenge.

Methods: This was a randomized, counterbalanced crossover study. Fifteen Division 1 collegiate basketball players (18-20 y) consumed 6.

Improvement of clinical outcome and cerebral perfusion in a patient of atherosclerotic cerebral infarction after repetitive hyperbaric oxygen treatment--a case report and literature review.

This is a case report of hyperbaric oxygen therapy (HBO2T) for ischemic stroke. HBO2T should be the potential or additional treatment (with thrombolytic therapy) for ischemic stroke according to the preclinical and clinical studies. Hereby, we present a 56-year-old Chinese man with vascular risk factors.

Interscapular hibernoma: case report and literature review.

Hibernoma is a rare benign tumor that arises from the vestiges of fetal brown fat. We present a case of interscapular hibernoma. Computed tomography scan showed a well-circumscribed, hypodense mass with peripheral enhancement, and magnetic resonance imaging revealed intermediate high T1 and T2 signal intensities with incomplete fat suppression.

Diabetic muscle infarction in a patient with acute embolic stroke.

Diabetic mellitus (DM) has many well-known complications. However, there is one rare complication, diabetic muscle infarction (DMI), which is usually under diagnosed. Hereby, we present a 53-year-old Chinese man with a history of DM, hypertension and atrial fibrillation.

Comparison of auto-moving table contrast-enhanced 3-D MRA and iodinated contrast-enhanced DSA for evaluating the lower-extremity arteries.

Background: This study was conducted to compare diagnostic efficacy of contrast-enhanced 3-dimensional magnetic resonance angiography (3-D MRA) with that of the conventional x-ray iodinated digital subtraction angiography (DSA) in patients with peripheral arterial occlusive diseases (PAOD).

Methods: Twenty patients with a clinical diagnosis of PAOD participated in this study. All patients were evaluated with both contrast-enhanced 3-D MRA and conventional x-ray iodinated DSA for the arteries of their lower extremities.

Carbon dioxide angiography in lower limbs: a prospective comparative study with selective iodinated contrast angiography.

This was a prospective comparison of the accuracy and image quality of carbon dioxide digital subtraction angiography (CO2 DSA) and iodinated contrast digital subtraction angiography (ICDSA) in evaluating lower extremity arteries and patient tolerance of the procedures. Selective DSA was performed in 14 Taiwanese patients who were diagnosed with peripheral artery occlusive disease (PAOD). Both contrast materials were administered through mechanical injectors.

Peritendinous lesions: the role of high-resolution ultrasonography.

Purpose: To evaluate the peritendinous lesions over the extremities by high-resolution ultrasonography (HRUS).

Materials And Methods: The authors retrospectively collected 328 cases, focusing on peritendinous lesions in limbs. The diagnosis was made by US findings with long-term follow-up, aspiration and biopsy proved.