Prospective Study Evaluating the Association Between sFlt-1/PlGF Ratio and Adverse Outcomes in Preterm Preeclampsia.

Objectives: To estimate the association between maternal soluble Fms tyrosine kinase 1 to placental growth factor (sFlt-1/PlGF) ratio and adverse outcomes related to preterm preeclampsia.

Methods: We performed a prospective study including participants with preeclampsia between 24 and 36 weeks of gestation. The sFlt-1/PlGF ratio was measured in maternal serum at admission and was reported according to pregnancy outcomes (delivery in <7 days after admission, severe preeclampsia before term, and serious complications, including stillbirth; eclampsia; hemolysis, elevated liver enzymes, and low platelet syndrome; and acute renal failure).

Diagnostic and therapeutic challenges of a rare large ovarian strumal carcinoid in pregnancy, about a case report.

Introduction: Ovarian strumal carcinoid is a rare type of germ cell tumor. It usually affects perimenopausal and postmenopausal women. Very few cases of stromal carcinoid have been reported in the literature in women of childbearing age, particularly during pregnancy.

Cornual Pregnancy: Results of a Single-Center Retrospective Experience and Systematic Review on Reproductive Outcomes.

: Cornual pregnancies (CPs) are rare forms of ectopic pregnancy. When abortion does not occur, it can be a life-threatening condition for the mother and can also impair future fertility. We present our experience in the diagnosis and management of CPs.

A non-pregnant woman with elevated beta-HCG: A rare case of ovarian seminoma.

Introduction: Ovarian seminoma is a rare germ cell tumor that typically affects young women. Early diagnosis of malignant tumors, although difficult due to mild symptoms, is crucial for a better prognosis. Here we report the case of a 15-year-old female patient with a large malignant ovarian dysgerminoma to provide a comprehensive overview of the diagnosis and management of this pathology and to help practitioners make an early diagnosis.

Secondary postpartum hemorrhage due to uterine scar dehiscence, a case report.

Introduction: Secondary postpartum hemorrhage is rare. The most common cause is retained placenta. Having a uterine scar dehiscence as an etiology is unusual.

The pentalogy of Cantrell: A rare and challenging prenatal diagnosis.

Introduction: The sternum, pericardium, diaphragm, abdominal wall, and heart are all affected by the unusual congenital condition known as Cantrell pentalogy. It is a rare congenital disorder that requires multidisciplinary care. Early diagnosis and appropriate management are crucial for improving outcomes in affected individuals.

Spontaneous subserosal venous rupture overlying a uterine leiomyoma in a young woman.

Uterine leiomyomas are very common tumors found in women. Rupture of veins on the surface of uterine leiomyoma is an unusual source of hemoperitoneum. It is an extremely uncommon gynaecological cause of hemoperitoneum.

How to adapt first trimester ultrasound education to Tunisian trainees.

Objectives: To evaluate the impact of a targeted training program on the quality of NT measures performed by OBST/GYN trainees.

Methods: Prospective study. Step1: each trainee achieved 10 T1US .

Fetopathological examination for the fetuses with Down syndrome in Tunisia: Epidemiological study and associated malformations.

Background: For Down syndrome (DS), traditional epidemiological studies to determine the prevalence, cause, and clinical significance of the syndrome have been conducted over the last 100 years. In Tunisia, the current work is the first in-depth study in epidemiology of DS from fetopathological data.

Aim Of The Study: The aim of this epidemiological study was to determine the impact of some feto-maternal characteristics in occurrence of DS and to search the frequency of associated congenital malformations with this syndrome.

[Which surgical strategy to adopt for the management of postpartum haemorrhage and how to improve the effects of hypogastric arteries ligation?].

The objective were to identify the success factors of bilateral hypogastric arteries ligation and to assess its role in surgical treatment of postpartum hemorrhages. We conducted a retrospective study of all the cases of postpartum hemorrhage requiring surgical treatment between January 2008 and December 2011. The study included 88 patients (0,47% of all births).

Vulvar cancer in Tunisia: Epidemiological and clinicopathological features multicentric study.

Objective: To describe for the first time the epidemiologic and clinico-pathologic characteristics of vulvar cancer in Tunisia.

Design: Two parts are distinguished in this study: Part1: Multicentric retrospective study about the characteristics of all cancer cases diagnosed during a 17-years period (January 1998-December 2014) in three departments of Gynecology and Obstetrics: one in south Tunisia and two in the capital. Part 2: To determine the Incidence trend of invasive vulvar cancer in North Tunisia 1994-2009, on the basis of North Cancer Registry of Tunisia.

Clinical Assessment of Soluble FMS-Like Tyrosine Kinase-1/Placental Growth Factor Ratio for the Diagnostic and the Prognosis of Preeclampsia in the Second Trimester.

Background: Preeclampsia is one of the most common and serious complications of pregnancy. Various reports have demonstrated that disturbances in angiogenic and antiangiogenic factors are implicated in its pathogenesis and have possible relevance in its diagnosis and prognosis.

Methods: In this case-control study, we enrolled 73 patients with 34 preeclamptic cases diagnosed according to clinical criteria and dosing of proteinuria.

[The contribution of ultrasonography in the exploration of postmenopausal metrorrhagias].

Post-menopausal metrorrhagias represent a frequent reason for consultation in gynecology. Our study aims to evaluate the contribution of pelvic ultrasonography in the exploration of endocavitary lesions in people experiencing this symptom and to compare the results found with those of hysteroscopy and histology. This was an analytic retrospective study of 33 cases referred for evaluation of postmenopausal metrorrhagias at the department of gynecology and obstetrics «A» in the Center of Maternity and Neonatology of Tunis in 2012.

Vitamin D Deficiency is Widespread in Tunisian Pregnant Women and Inversely Associated with the Level of Education.

Background: Vitamin D deficiency seems to be common in pregnant women and would be associated with an increased risk of maternal and fetal poor outcomes. This study aimed to determine the prevalence and the main risk factors for vitamin D deficiency in pregnant women living in a sun-rich environment.

Methods: A total of 255 pregnant women living in Tunis City (latitude, 36 degrees N) were randomly selected at 12 - 18 weeks of gestation.

[Breech presentation: Does the decision of vaginal delivery depend on parity?].

Background: The breech presentation delivery mode is still controversial. The cesarean section is becoming the current trend especially in case of primiparous.

Aim: To compare the maternal and fetal prognosis of the breech presentation delivery according to the parity.

Ovarian vein thrombosis.

Ovarian vein thrombosis (OVT) is a rare cause of abdominal pain that may mimic a surgical abdomen. It is most often diagnosed during the postpartum period. In this report, we present four cases of postoperative ovarian vein thrombosis.

Desmoid tumors: clinical features and treatment options: a case report and a review of literature.

Desmoid tumors are a rare group of locally aggressive, non malignant tumors of fibroblastic origin that can lead to significant morbidity due to local invasion and may even result in a fatal outcome when located around vital organs. Their clinical presentation, biological behavior and natural history can be quite varied and is incompletely understood at the present time. The optimal therapeutic approach depends on various factors, and a multidisciplinary approach is necessary to achieve local control with acceptable morbidity.

[Audit of sterilization practices in two Tunisian hospitals: current situation and perspectives].

Background: In most Tunisian hospitals, medical devices (MD) are sterilized at surgical or medicine departments.

Aim: to overview during one month the practice of sterilization. aterial

Methods: An audit of practices through direct observation was carried out at the neonatology and gynaecology departments at the Maternity and Neonatology Center of Tunis and the surgical department at the Salah Azaïz Institute.

Fetopathological aspects of holoprosencephaly.

Unlabelled: Holoprosencephaly (HPE) is a congenital central nervous system malformation estimated to occur in 1/250 conceptuses and 1/10,000 live births. While the severe forms, which are incompatible with life, are easier to detect in the prenatal period, the milder forms can remain unrecognised. As this can have serious consequences for the pregnancy and malformation carriers it is of crucial importance to find ways of timely detection of this pathological condition.

[Obstetric vesicovaginal fistulas, about 131 cases].

Background: Vesicovaginal fistulas are the most frequent type of urogenital fistulas. Obstetrical cause remains the dominant etiology. They still represent a public health problem.

[First trimester ultrasound: an early screening tool for fetal structural and chromosomal abnormalities].

Background: Prenatal diagnosis has been greatly expanded in recent years. Many biological and sonographic criteria participated in the development of fetal medicine.

Aim: Analyze the contribution of first trimester ultrasound in prenatal diagnosis of aneuploidy and early fetal malformations, and its impact on the strategy of prevention of disability.