Publications by authors named "Charlotte Addy"
Background: The NHS Patient Safety Syllabus highlights human factors as a core education theme for all healthcare staff. Despite this, no multidisciplinary Human Factors courses in NHS Wales have previously been reported.
Approach: A multidisciplinary Human Factors course was created and delivered by a faculty with varied clinical and teaching backgrounds.
This is the final of four papers updating standards for the care of people with CF. That this paper "Planning a longer life" was considered necessary, highlights how much CF care has progressed over the past decade. Several factors underpin this progress, notably increased numbers of people with CF with access to CFTR modulator therapy.
View Article and Find Full Text PDFArticle Synopsis
- - This paper is part of a series updating standards of care for cystic fibrosis (CF), emphasizing the importance of recognizing and managing various CF health issues despite advancements like CFTR modulators.
- - It highlights the need for multidisciplinary care to address ongoing extrapulmonary issues such as diabetes, liver disease, and increased cancer risk, which require regular screenings.
- - Mental and emotional support is crucial for individuals with CF and their families, especially during challenging times, and planning for end-of-life care should be approached with sensitivity and compassion.
Standards for the care of people with cystic fibrosis; establishing and maintaining health.
J Cyst Fibros
January 2024
This is the second in a series of four papers updating the European Cystic Fibrosis Society (ECFS) standards for the care of people with CF. This paper focuses on establishing and maintaining health. The guidance is produced using an evidence-based framework and with wide stakeholder engagement, including people from the CF community.
View Article and Find Full Text PDFStandards for the care of people with cystic fibrosis (CF): A timely and accurate diagnosis.
J Cyst Fibros
November 2023
Article Synopsis
- Advances in cystic fibrosis (CF) diagnosis focus on improvements in newborn bloodspot screening, gene analysis, and understanding CFTR-related disorders.
- These developments highlight the importance of timely and accurate diagnosis for access to variant-specific therapy, which can significantly benefit those with eligible CFTR gene variants.
- The guidance in this paper updates previous standards and emphasizes the growing necessity for proper diagnosis as future trials for variant-specific therapies are anticipated.
British Thoracic Society survey of the career intentions of respiratory medicine specialty trainees in the UK.
BMJ Open Respir Res
April 2022
There were respiratory consultant post vacancies in 82% of surveyed UK hospitals in 2021. Understanding respiratory trainees' career intentions is vital to plan and train a future respiratory workforce. In 2020, the British Thoracic Society surveyed trainee members (n=144) to assess career plans and perceived barriers and facilitators when applying for consultant posts.
View Article and Find Full Text PDFRationale: Sputum biomarkers hold promise as a direct measure of inflammation within the cystic fibrosis (CF) lung, but variability in study design and sampling methodology have limited their use. A full evaluation of the reliability, validity and clinical relevance of individual biomarkers is required to optimise their use within CF clinical research.
Objectives: A biomarker Special Interest Working Group was established within the European Cystic Fibrosis Society-Clinical Trials Network Standardisation Committee, to perform a review of the evidence regarding sputum biomarkers in CF.
British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease.
BMJ Open Respir Res
April 2020
Article Synopsis
- The British Thoracic Society (BTS) published new guidelines on long-term use of macrolides for adults with respiratory diseases, available in the journal Thorax.
- The summary includes key recommendations and best practices, referencing specific sections of the comprehensive guideline.
- This guideline is the first to adopt the GRADE methodology for evaluating and grading recommendations, marking a pilot for the BTS in this new approach.
The Gram-negative bacterium, , is a major respiratory pathogen in patients with cystic fibrosis (CF), with an associated increase in morbidity and mortality. Consequently, infection prevention and control (IPC) plays an important role within health care in order to minimize the risk of cross-infection of this organism amongst patients and the hospital environment. It was the aim of this study to examine bacterial contamination of the health estate of CF in-patients' single-bedded rooms and related environments (n=40).
View Article and Find Full Text PDFPutting CHIP(s) on the Table: Introducing Nitrosothiols into the Arena of CFTR Modulation.
Am J Respir Cell Mol Biol
December 2019