Publications by authors named "Chaopeng Chen"
Perianal leiomyosarcoma as a rare sequela of rectal cancer radiotherapy: a case report.
Front Oncol
November 2024
Radiation-induced sarcomas (RIS) are iatrogenic malignancies that arise following high-dose radiotherapy, posing a significant clinical challenge due to their poor prognosis and resistance to conventional treatments. The incidence of RIS is increasing with advancements in radiotherapy techniques. This report presents a case of a 71-year-old male diagnosed with stage III rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and curative surgery.
View Article and Find Full Text PDFConcurrent EGFR mutation and SMARCA4 deficiency in non-small cell lung cancer: A case report and literature review.
Medicine (Baltimore)
October 2024
Article Synopsis
- SMARCA4-deficient non-small cell lung cancer (NSCLC) is aggressive and usually has a poor prognosis, with rare co-occurrences of actionable mutations like EGFR or ALK alongside it.* -
- A 79-year-old female patient was diagnosed with this type of lung cancer, featuring an EGFR exon 21 L858R mutation, leading to a unique treatment challenge.* -
- Initial treatment with osimertinib gave partial remission, but after disease progression, a combination therapy with anlotinib stabilized the patient's condition temporarily, highlighting the need for ongoing adjustments in treatment strategies.*