Anterior chamber depth measurement in phakic and pseudophakic eyes.

Purpose: To compare anterior chamber depth (ACD) measurements using two non-contact optical devices, Pentacam and IOLMaster, and a contact device, ultrasonic A-scan in phakic and pseudophakic eyes.

Methods: Ninety phakic and 94 pseudophakic eyes were enrolled in this prospective study. The difference between ACD measurements by the three devices was analyzed using the repeated-measures analysis of variance, and agreement among the three measurements was investigated.

Intraocular lens power calculation using the IOLMaster and various formulas in eyes with long axial length.

Purpose: To evaluate the predictability of intraocular lens (IOL) power calculations using the IOLMaster (Carl Zeiss) and different IOL power calculation formulas in eyes with a long axial length (AL).

Setting: Department of Ophthalmology, Far Eastern Memorial Hospital, Taipei, Taiwan.

Methods: This study included 68 eyes with an AL longer than 25.

Managing keratoconus with reverse-geometry and dual-geometry contact lenses: a case report.

Purpose: To present a case of keratoconus successfully managed with various rigid gas-permeable contact lenses with reverse-geometry and dual-geometry designs.

Methods: Case report.

Results: The steepest topographic keratometric readings of a 30-year-old woman with keratoconus were 62.

Egr1 gene knockdown affects embryonic ocular development in zebrafish.

Purpose: To identify the changes in zebrafish embryonic ocular development after early growth response factor 1 (Egr1) gene knockdown by Egr1-specific translation inhibitor, morpholino oligonucleotides (MO).

Methods: Two kinds of Egr1-MO were microinjected separately with various dosages into one to four celled zebrafish embryos to find an optimal dose generating an acceptable mortality rate and high frequency of specific phenotype. Chordin-MO served as the positive control; a 5 mismatch MO of Egr1-MO1 and a nonspecific MO served as negative controls.

Analysis of crystalline lens position.

Purpose: To study normal crystalline lens position to provide a comparative baseline for future studies of crystalline lens or intraocular lens shift.

Setting: Taipei Municipal Yang-Ming Hospital, Taipei, Taiwan.

Methods: A Scheimpflug anterior segment analyzer (EAS-1000, Nidek) was prospectively applied to measure the cycloplegic crystalline lens position in subjects who had not had previous ocular surgeries or who had been diagnosed previously with major ocular diseases such as glaucoma, retinal detachment, or cataract.

Clinical characteristics and leakage of functioning blebs after trabeculectomy with mitomycin-C in primary glaucoma patients.

Purposes: To describe the clinical characteristics of functioning blebs in Japanese glaucoma patients after primary trabeculectomy with adjunctive mitomycin-C (MMC) and to correlate their associations with postoperative bleb leakage.

Design: A prospective, observational case series.

Participants: One hundred sixty-two glaucoma patients who had undergone primary trabeculectomy with MMC at the University of Tokyo Hospital at least 3 months before were examined between December 1997 and February 1998.