Challenges in Diagnosing Systemic Amyloidosis.

Background: The diagnosis of cardiac amyloidosis can be achieved noninvasively for transthyretin amyloid cardiomyopathy through nuclear scintigraphy with bone tracers. For other subtypes of cardiac amyloidosis (eg, light-chain amyloid cardiomyopathy), or in cases of suspected transthyretin amyloid cardiomyopathy with nondiagnostic scintigraphy results, histologic confirmation via tissue biopsy and amyloid subtype identification is required.

Case Summary: We present a case of a 66-year-old male with heart failure and left ventricular hypertrophy with evidence of systemic amyloidosis.

Kikuchi-Fujimoto disease - a case report of a paediatric patient.

Kikuchi-Fujimoto disease is usually a self-limited cause of lymphadenitis. It is a prevalent disease amongst Asian individuals, but rare in other parts of the world. It affects especially young women, with limited cases described in children.