Injectable-Only Overlapping Buprenorphine Starting Protocol in a Low-Threshold Setting.

Importance: Initiating buprenorphine for opioid use disorder (OUD) in outpatient settings has become more difficult for individuals using fentanyl. Novel buprenorphine starting strategies are needed, especially for people experiencing homelessness.

Objective: To evaluate the short-term outcomes of the implementation of an injectable-only overlapping buprenorphine starting protocol in a low-threshold clinic and field-based setting serving individuals with OUD and active fentanyl use.