Publications by authors named "Carla Massignan"

Periodontitis is considered an inflammatory disease that affects the tooth's supporting structures, resulting in its progressive destruction, which can lead to several problems, such as loss of teeth, bone reabsorption, and even exacerbation of chronic systemic diseases. Periodontitis is a common periodontal condition in the adult dentate population, affecting approximately 6 in 10 individuals. Among those affected, approximately 25% develop the most severe form of the disease.

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Objectives: Although pulpectomy is recommended as the choice treatment for primary teeth with pulpal involvement, some clinicians and parents consider tooth extraction a viable option. This systematic review aimed to assess the impact of pulpectomy versus extraction of primary teeth on patient-centered outcomes.

Methods: Seven electronic databases and grey literature were searched on April 05, 2024.

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Removal of the buccal fat pad can be considered safe as long as there is a detailed analysis of anatomical landmarks. The objective of this study was to estimate the prevalence of intra- and postoperative complications resulting from buccal fat pad removal through a systematic review. The search strategy involved observational and/or interventional studies in humans that included at least one case of buccal fat pad removal with a description of the surgery, postoperative progress, and complications.

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Article Synopsis
  • - The study explores bruxism's complex origins, noting that both genetic and non-genetic factors contribute to its development, but the role of genetic markers is still not well understood.
  • - Researchers analyzed 21 reports, including 16 original studies, focusing on genetic associations with sleep bruxism (SB) and awake bruxism (AB), identifying 15 significant genetic polymorphisms across 11 genes.
  • - Findings suggest specific genes associated with SB (like serotonergic and dopaminergic pathways) and AB (like ACTN3 and ANKK1), indicating potential genetic influences but highlighting the need for further research.
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Background: Leukemia is the most common malignancy in pediatric patients, and it has extramedullary involvement. Oral manifestations have been reported in the literature, but to the authors' knowledge, no systematic review has presented the general prevalence of these manifestations. This review aimed to determine the prevalence of oral manifestations in pediatric patients with leukemia.

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Background/aim: Crown fractures are common traumatic dental injuries and tooth fragment reattachment is a viable option for restoring a fractured tooth. The aim of this study was to assess the knowledge and experience of dentists in the Federal District regarding the tooth fragment reattachment technique for enamel and dentin fractures.

Materials And Methods: For the cross-sectional observational study, an electronic form was designed with objective and self-report questions for dentists.

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Objectives: To identify the prevalence of Awake Bruxism (AB).

Sources: The electronic search was done in Embase, PubMed/MEDLINE, LILACS, Livivo, Scopus, and Web of Science databases up to January 2nd, 2023. The search strategies combined terms such as "bruxism," "awake," and related terms when conducting searches in databases.

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Background: The purpose of this systematic review was to assess the clinical efficacy (sensitivity reduction) and safety (gum damage) of silver diamine fluoride (SDF) as a tooth desensitizer for adults.

Methods: The search strategy was developed and adapted from 12 databases. Two independent reviewers selected the studies in consensus with a third reviewer.

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There is a need to investigate methods to increase children's health knowledge. Therefore, the aim of this study was to systematically evaluate the literature on playful educational interventions in health literacy aimed at children aged 6-12 years. For this purpose, the Cochrane Library, EMBASE, LILACS, PubMed, Scopus, Web of Science and grey literature were searched for relevant studies.

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Article Synopsis
  • The study examined the global prevalence of natal (teeth present at birth) and neonatal (teeth appearing within the first month) teeth, highlighting their importance for immediate care.
  • A total of 23 studies were analyzed, showing a worldwide prevalence of 34.55 natal teeth and 4.52 neonatal teeth per 10,000 newborns; significant variations were found across different continents.
  • Despite the low occurrence rates (around 1 in 289 for natal teeth and 1 in 2,212 for neonatal teeth), healthcare professionals need to be vigilant in recognizing these conditions for timely intervention.
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Background: Non-nutritive sucking habits likely may cause occlusal changes such as anterior open bite (AOB) if they persist over extended time.

Objectives: To assess if there is self-correction of AOB after cessation of non-nutritive sucking habits in children older than 4 years old, through a systematic review.

Search Methods: Data sources included PubMed, Scopus, Web of Science and Latin American and Caribbean Health Sciences (LILACS) databases, gray literature as Google Scholar, the database System for Information on Gray Literature in Europe (OpenGrey) and ProQuest Dissertations and Theses Database, also hand searches of the included studies references.

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Background: Parents believe that teething is associated with signs and symptoms, which may induce them to give medications that could harm their children. Some children may require alleviation of symptoms and overall attention.

Aim: To assess parents' beliefs in and attitudes toward teething.

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Article Synopsis
  • The study aimed to assess dentists' knowledge, attitudes, and practices regarding Minimal Intervention Dentistry (MID) through a systematic review of relevant literature.
  • A total of 2079 studies were screened, with 12 being included for analysis, revealing that while dentists had a good level of knowledge (75.66%), their attitudes and practices were significantly lower (47.95%).
  • The researchers concluded that although dentists are knowledgeable about MID, improvements are needed in their attitudes and practices, and called for more standardized studies to better understand this issue globally.
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Introduction: The overall prevalence of maxillary sinusitis of odontogenic origin (MSOO) is still unknown. Therefore, this study aimed to determine the pooled prevalence of MSOO and verify associations between different odontogenic conditions and MSOO.

Methods: Six electronic databases and the gray literature were searched on August 25, 2022.

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Objectives: This systematic review aimed to answer the following question 'What are the worldwide prevalence of SARS-CoV-2 infection and associated factors among oral health-care workers (OHCWs) before vaccination?'

Methods: Seven databases and registers as well as three grey databases were searched for observational studies in the field. Paired reviewers independently screened studies, extracted data and assessed the methodological quality. Overall seroprevalence for SARS-CoV-2 infection was analysed using a random-effect model subgrouped by professional category.

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Article Synopsis
  • The study investigated how parents accept various pediatric behavior guidance techniques (BGTs) used during dental visits for their children, comparing responses from parents of both special health care needs (SHCN) and non-special health care needs (non-SHCN) children.
  • A total of 53 studies with 4,868 participants were analyzed, showing a wide range of acceptance rates, from 85.6% for the tell-show-do technique down to only 25.7% for passive protective stabilization among non-SHCN parents.
  • Overall, the findings indicate that parents generally prefer simpler BGTs over more complex methods, but the heterogeneity among studies leads to low confidence in the conclusions.
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  • This study evaluated the effectiveness of artificial intelligence (AI) in deciding whether to extract teeth in orthodontic cases, emphasizing its accuracy in decision-making.
  • The researchers analyzed data from various databases and included six relevant studies, revealing mixed risk levels of bias among them.
  • While AI showed a promising overall accuracy rate of 0.87, the findings should be approached cautiously due to low certainty in the evidence, and AI should not replace human judgment in orthodontic decisions just yet.
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Article Synopsis
  • The study aimed to determine the prevalence of geographic tongue in adults over 18 by reviewing population-based observational studies.
  • A systematic search of multiple databases and gray literature identified 3046 studies, ultimately narrowing down to 11 for quantitative analysis.
  • The findings showed a prevalence of about 3%, indicating that approximately 1 in 30 adults has geographic tongue, with consistency in prevalence during different phases of the condition.
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Background: Animal-assisted therapy (AAT) is considered a useful technique to reduce anxiety in children and adolescents in medical settings.

Aim: To investigate whether the use of AAT helps to reduce anxiety during dental care in children and adolescents.

Design: Systematic review that included randomized and nonrandomized clinical trials with children up to 18-years of age undergoing dental appointments.

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Objective: Burnout syndrome has negative consequences on the dentist's health and performance during work. This systematic review aimed to assess the prevalence of Burnout syndrome in dentists.

Methods: Searches were carried out in Medline, Scopus, Web of Science, PsycINFO, EMBASE, LILACS databases, and searches in the gray literature on January 27, 2021.

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Introduction The number of systematic reviews (SRs) in dentistry published each year has grown considerably, and they have been essential in clinical decision-making and health policy.Objective The objective is to critically appraise SRs of intervention in dentistry using the 'A Measurement Tool to Assess Systematic Reviews 2' (AMSTAR 2) tool published within one year.Methods A search in the Medline/PubMed database was performed.

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Objectives: The use of natural products for pulp therapy has experienced a remarkable advancement in recent years. The aim was to provide a critical appraisal of the safety and efficacy of natural products for endodontic therapy in primary teeth and verify whether their uses in clinical practice have sufficient evidence.

Materials And Methods: Two reviewers searched ten databases (Cochrane, DOSS, Embase, Google Scholar, LILACS, OpenGrey, Proquest, PubMed, Scopus, and Web of Science) until January 2022, identifying references that evaluated the safety and efficacy of the use of natural products for endodontic therapy in primary teeth.

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Background: The lack of a well-defined apical constriction in primary teeth raises concerns regarding the accuracy of electronic apex locators (EALs) for measuring working length.

Objectives: To evaluate the accuracy of EALs in determining working length in primary teeth pulpectomies.

Methods: Two reviewers searched ten databases up to September 2021.

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Study Objectives: To evaluate the available evidence on the putative relationships between sleep bruxism (SB) and, obstructive sleep apnea (OSA) to assess the extent of research on this topic, and to formulate suggestions for future research.

Methods: A scoping review including studies examining temporal and overall association and prevalence of SB and OSA was performed. Six main databases and gray literature were searched.

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Objective: To assess effects of stabilization splints on signs and symptoms of temporomandibular disorders of muscular origin compared to other treatments.

Methods: A search for articles via six electronic databases and gray literature was conducted. The risk of bias was evaluated with the Cochrane Collaboration tool.

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