Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study.

Background: Reliable dosimetry based on SPECT/CT imaging is essential to achieve personalized Ho-radioembolization treatment planning and evaluation. This study quantitatively evaluates multiple acquisition and reconstruction protocols for Ho-SPECT imaging based on data from five Dutch hospitals. We aim to recommend an imaging protocol which harmonizes Ho-SPECT images for reproducible and accurate dosimetry in a multi-scanner and multi-center setting.

Comparative image quality and dosimetric performance of two generations of dedicated breast CT systems.

Background: Dedicated breast computed tomography (bCT) systems offer detailed imaging for breast cancer diagnosis and treatment. As new bCT generations are developed, it is important to evaluate their imaging performance and dose efficiency to understand differences over previous models.

Purpose: To characterize the imaging performance and dose efficiency of a second-generation (GEN2) bCT system and compare them to those of a first-generation (GEN1) system.