Shear wave elastography provides reliable assessments of stiffness in the skin, fascia, and both superficial and deep muscle tissues.

Shear wave elastography (SWE) is a reliable method of estimating stiffness of superficial rectus femoris (RF) muscle at various muscle lengths. Its reliability has not been assessed in deeper muscle regions or its overlying fascia and skin tissue. 20 healthy participants completed two visits in which RF shear wave velocity (SWV) was measured twice, separated by 30mins, at four depths (skin-SKIN, fascia-FAS, superficial muscle-SUP, and deep muscle-DEEP) in three positions (relaxed-REL, neutral-NEU, and stretched-STR).

MyotonPRO Is Not Comparable to Shear Wave Elastography in the Measurement of Rectus Femoris Muscle Stiffness due to Interference of Subcutaneous Adipose Tissue.

Tissue biomechanical properties are important for optimizing musculoskeletal performance and reducing injury risk. The MyotonPRO was developed as a simple, portable, noninvasive, and highly reliable method for the estimation of muscle stiffness. It has not, however, been comprehensively validated against shear wave elastography (SWE), a validated ultrasound-based method for assessing tissue stiffness.

The emerging role of heterodimerisation and interacting proteins in ghrelin receptor function.

Ghrelin is a peptide hormone secreted primarily by the stomach that acts upon the growth hormone secretagogue receptor (GHSR1), a G protein-coupled receptor whose functions include growth hormone secretion, appetite regulation, energy expenditure, regulation of adiposity, and insulin release. Following the discovery that GHSR1a stimulates food intake, receptor antagonists were developed as potential therapies to regulate appetite. However, despite reductions in signalling, the desired effects on appetite were absent.