Short- and Long-Term Effects of Adding Topical Cosmetics to a Dermatological Procedure (Thermage): A Randomized Controlled Comparative Study Exploring the Synergistic Effects.

Background: Dermatological procedures improve skin changes caused by aging. However, few studies have focused on the effect of improving various skin characteristics compared with the concurrent use of cosmetics. We aimed to confirm changes in skin characteristics owing to anti-aging dermatological procedures in the short- and long-term and to determine the efficacy of the procedure when products with anti-aging and repair effects are used together.

Development and application of artificial intelligence-based facial skin image diagnosis system: Changes in facial skin characteristics with ageing in Korean women.

Objective: To develop and validate an artificial intelligence (AI)-based diagnostic system for analysing facial skin images using expert judgements and explore its feasibility for skin ageing research, specifically by evaluating facial skin changes in Korean women of various ages.

Methods: Our AI-based facial skin diagnosis system (Dr. AMORE®) uses facial images of Korean women to analyse wrinkles, pigmentation, skin pores, and other skin red spots.

A long term study of the difference in efficacy and effect rate of various concentrations of retinol (1500-6600 IU) in middle aged women.

Retinol is widely used for topical application for antiaging. However, the efficacy and effect rate of different concentrations of retinol have been rarely analyzed. Therefore, in this study, the efficacy and rate of effect of retinol concentrations from 1500 to 6600 IU, on various skin parameters, have been compared.

Effects of one year of daily face mask wearing on the skin during the coronavirus disease 2019 pandemic.

Background: As coronavirus disease 2019 (COVID-19) continues, the long-term daily use of masks is increasing. A full year includes the four seasons of spring, summer, autumn, and winter. Skin may have been affected by the seasons and further affected by the use of masks.

Skin biophysical properties including impaired skin barrier function determine ultraviolet sensitivity.

Background: The levels of burning susceptibility to ultraviolet (UV) radiations are affected by various factors, including Fitzpatrick skin types, skin color, sex, and ethnicity. However, studies on the relationship between skin biophysical properties and erythemal responses to UV radiations are rare.

Objective: This study aimed to investigate biophysical properties of the skin that determined individual skin sensitivity to UV radiation.

Long-term effects of face masks on skin characteristics during the COVID-19 pandemic.

Background: Nowadays, face masks are a crucial part of our daily life. Previous studies on their impact on the skin usually focused on the adverse effects of face masks. Few studies have assessed their influence on skin characteristics.

Evaluation of changes in skin characteristics due to the poor quality of sleep caused by smartphone usage.

Background: Blue wavelengths are thought to have an effect on circadian rhythms. Using a smartphone, which emits a 453 nm blue light, can worsen the quality of sleep.

Aims: To study the skin changes caused by poor sleep quality induced by smartphone usage.

Efficacy of ethyl ascorbyl ether-containing cosmetic cream on blue light-induced skin changes.

Background: Office workers are consistently exposed to blue light, mainly from sunlight and digital device. Recent studies report that blue light has various harmful effects, including cellular changes via reactive oxygen species. Studies on blue light-induced skin changes have only been conducted in vitro and have not been clinically confirmed.

Skin characteristics following repeated exposure to simulated outdoor and indoor summer temperatures in South Korea and Southeast Asia.

Background: Although changes in skin depend on the external environment, researchers have performed only a few studies on effect of the actual environment. Most studies have researched skin characterization based on changes in the humidity or temperature.

Aim/objective: This study aimed to evaluate changes in the skin based on the difference in indoor and outdoor temperatures and humidity during summer in South Korea and Southeast Asia.

Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women.

Background: Skin darkening because of increased and irregular synthesis of melanin causes melasma, solar lentigo, and freckles. Melasolv™, produced in the early 2000s, shows potent depigmenting effect and has low cytotoxicity. It has been used as a brightening agent in cosmetics for decades.

Clinical evaluation method for blue light (456 nm) protection of skin.

Background: Blue light from electronic devices enriched with a peak at 456 nm affects circadian rhythm and antioxidant balance of skin, necessitating the study of photoprotection against the 456-nm blue light.

Aims: This study aims to report that blue light (456 nm) can cause skin pigmentation and proposes a new clinical evaluation method for blue light (456 nm) protection based on the skin pigmentation level.

Patients/methods: We developed a clinical device (ABC device ) that emits blue light (peak = 456 nm).