Applicability of the daily hydrological models (GR4J, GR5J, and GR6J) in the South Korean basins.

Despite the increasing frequency of extreme droughts caused by climate change, which prompts a reevaluation of the need for low-flow simulation, there is a lack of evaluation of low-flow estimation using GR5J and GR6J models in Korean basins compared to studies on GR4J. This study assesses the applicability of the GR5J and GR6J models in South Korean basins. It aims to determine how to calibrate these models effectively in South Korea.

Low-density lipoprotein cholesterol and clinical outcomes in patients with liver cirrhosis: a nationwide cohort study.

Background: The association between low-density lipoprotein cholesterol (LDL-C) levels and clinical outcomes in patients with liver cirrhosis (LC) remains unclear. In this study, we aimed to investigate the association between LDL-C levels and cardiovascular events, along with all-cause death in patients with LC, using a nationwide database.

Materials And Methods: This retrospective cohort study included 303,988 patients with LC identified from the Korean National Health Insurance Service database who underwent health examinations between 2009 and 2017.

The impact of sleep health on cardiovascular and all-cause mortality in the general population.

Sleep patterns are important predictors of long-term health outcomes. We investigated the associations of sleep duration, sleep regularity, and their combinations with all-cause mortality and cardiovascular events in a large Korean cohort, including sex-specific analyses. This prospective cohort study included 9,641 adults aged 40-69 years from the Ansung-Ansan cohort in Korea.

Associations Between Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Outcomes in Patients Undergoing Dialysis: A Nationwide Cohort Study.

Low-density lipoprotein cholesterol (LDL-C) is a causal factor in the development of atherosclerosis and a predictor of cardiovascular disease. However, the association between LDL-C levels and cardiovascular outcomes in patients undergoing dialysis remains controversial, with current guidelines advising against initiating statin therapy in this population. This study investigated the relationship between LDL-C levels and cardiovascular outcomes in Korean adults undergoing dialysis, using nationwide data.

Hepatic Steatosis in Cardiovascular-Kidney-Metabolic Syndrome: Fatty Liver Index as a Predictor of Cardiovascular Outcomes.

Aims: Cardiovascular-kidney-metabolic (CKM) syndrome describes the interplay between metabolic dysfunction, chronic kidney disease, and cardiovascular disease. While this framework advances our understanding of interrelated pathophysiology across multiple organ systems, further exploring the liver's role may be beneficial. The fatty liver index (FLI) is a cost-effective indicator of hepatic steatosis; however, its prognostic role in CKM syndrome remains unclear.

Longitudinal Changes in Cardiovascular-Kidney-Metabolic Syndrome Stages and Their Impact on Outcomes: A Nationwide Cohort Study.

The impact of longitudinal changes in cardiovascular-kidney-metabolic (CKM) stage remains unclear. This study evaluated the association between CKM stage progression and clinical outcomes. : We used the Korean National Health Insurance Database to identify adults aged ≥ 20 years who underwent two health checkups between 2009 and 2012.

Machine learning approach for identifying and forecasting streamflow droughts in data limited basins of South Korea using threshold levels.

Artificial Intelligence (AI) has been extensively utilized for streamflow prediction, primarily in gauged watersheds using meteorological and historical streamflow data. However, its application in data-limited regions requires innovative approaches due to the reliance on extensive monitoring data. Physically based models, while comprehensive, are labor-intensive and inherently uncertain.

Impact of blood pressure and medication adherence on clinical outcomes in patients with hypertension.

Background: Hypertension is a key risk factor for cardiovascular disease. Thus, effective blood pressure (BP) management and adherence to antihypertensive medications are crucial for reducing these risks in patients with hypertension. We evaluated the effect of BP and medication adherence on the clinical outcomes of patients with hypertension.

Association of systolic blood pressure target and variability with long-term clinical outcomes in patients undergoing percutaneous coronary intervention.

Background: The combined impact of achieving target systolic blood pressure (SBP) and blood pressure variability (BPV) on long-term clinical outcomes in patients with coronary artery disease following percutaneous coronary intervention (PCI) remains unclear. This study aimed to investigate the combined effect of SBP target achievement and BPV on the risk of cardiovascular events in patients undergoing PCI.

Methods: Consecutive patients who underwent PCI between 2012 and 2016 were included.

Comparing blood pressure measurements between sitting in chairs and sitting on the floor.

Background: The current standard approach to measuring home blood pressure (BP) involves taking measurements while sitting in a chair. In cultures where floor sitting is common, including Korea, assessing BP while sitting on the floor would be more feasible. However, there is still a lack of research investigating whether BP measurements obtained while seated in a chair and while sitting on the floor can be regarded as interchangeable.

Long-term prognostic implications of brachial-ankle pulse wave velocity in patients undergoing percutaneous coronary intervention.

Objective: The long-term clinical effect of arterial stiffness in high-risk disease entities remains unclear. The prognostic implications of brachial-ankle pulse wave velocity (baPWV) were assessed using a real-world registry that included patients who underwent percutaneous coronary intervention (PCI).

Methods: Arterial stiffness was measured using baPWV before discharge.

Estimated pulse wave velocity as a forefront indicator of developing metabolic syndrome in Korean adults.

Background/aims: The predictive value of the estimated pulse wave velocity (ePWV) for the development of metabolic syndrome has not yet been extensively explored. This study aimed to fill this gap by evaluating ePWV as a potential predictor of metabolic syndrome development in middle-aged Korean adults.

Methods: Using prospective data obtained from the Ansan-Ansung cohort database, participants without metabolic syndrome at baseline were studied.

Harnessing Metabolic Indices as a Predictive Tool for Cardiovascular Disease in a Korean Population without Known Major Cardiovascular Event.

Backgruound: This study evaluated the usefulness of indices for metabolic syndrome, non-alcoholic fatty liver disease (NAFLD), and insulin resistance (IR), as predictive tools for cardiovascular disease in middle-aged Korean adults.

Methods: The prospective data obtained from the Ansan-Ansung cohort database, excluding patients with major adverse cardiac and cerebrovascular events (MACCE). The primary outcome was the incidence of MACCE during the follow-up period.

Blood pressure and variability responses to the down-titration of antihypertensive drugs.

Objectives: Several recent guidelines have proposed the gradual reduction of antihypertensive drugs for patients with well controlled blood pressure (BP). However, no studies have examined alterations in BP variability (BPV) during the down-titration of antihypertensives. This study aims to investigate changes in home BPV during the down-titration of antihypertensives.

Association between Estimated Pulse Wave Velocity and Incident Nonalcoholic Fatty Liver Disease in Korean Adults.

Introduction: Nonalcoholic fatty liver disease (NAFLD) is associated with vascular dysfunction, one of the signs of which is arterial stiffness. Carotid-femoral pulse wave velocity (PWV), which is considered the gold standard measure of arterial stiffness, can be estimated using two commonly assessed clinical variables: age and blood pressure. This study aimed to evaluate the association between estimated PWV (ePWV) and the prevalence and incidence of NAFLD among Korean adults.

Effect of low sodium and high potassium diet on lowering blood pressure and cardiovascular events.

Incorporating aggressive lifestyle modifications along with antihypertensive medication therapy is a crucial treatment strategy to enhance the control rate of hypertension. Dietary modification is one of the important lifestyle interventions for hypertension, and it has been proven to have a clear effect. Among food ingredients, sodium and potassium have been found to have the strongest association with blood pressure.

Electrocardiography score based on the Minnesota code classification system predicts cardiovascular mortality in an asymptomatic low-risk population.

Background: The use of a single abnormal finding on electrocardiography (ECG) is not recommended for stratifying the risk of cardiovascular (CV) events in low-risk general populations because of its low discriminative power. However, the value of a scoring system containing multiple abnormal ECG findings for predicting CV death has not been sufficiently evaluated.

Methods: In a prospective community-based cohort study, 8417 participants without atherosclerotic CV diseases (ASCVDs) and any related symptoms were followed for 18 years.

Prior bariatric surgery and risk of poor in-hospital outcomes in COVID-19: findings from a National Inpatient Sample.

Background: Obesity and obesity-related co-morbidities are risk factors for severe coronavirus disease 2019 (COVID-19).

Objectives: As bariatric surgery effectively addresses obesity-related conditions, we hypothesized that prior bariatric surgery may be associated with a reduced risk of severe COVID-19. Small-scale studies have suggested favorable outcomes; however, large-scale nationwide database studies are scarce.

Clinical and life style factors related to the nighttime blood pressure, nighttime dipping and their phenotypes in Korean hypertensive patients.

Background: Non-dipping or reverse dipping patterns are known to be associated with adverse cardiovascular prognosis among the general population and clinical cohort. Few large sized studies have explored factors including sleep duration and sleep quality related to nighttime blood pressure (BP) and nocturnal dipping patterns.

Methods: Among 5,360 patients enrolled  in Korean multicenter nationwide prospective Registry of ambulatory BP monitoring (KORABP), 981 subjects with complete data on sleep duration, sleep quality assessed using a 4-point Likert scale, and clinical variables were included in the analysis.

Quantitative measurement of empathy and analysis of its correlation to clinical factors in korean patients with chronic diseases.

Background: Empathy is the core of the physician-patient relationship. The Consultation and Relational Empathy (CARE) measure is a useful tool for assessing patient-rated empathy. There have been scarce data on empathy in chronic disease patients in Korea.

Association between D-dimer and long-term mortality in patients with acute severe hypertension visiting the emergency department.

Objective: High levels of D-dimer, a marker of thrombotic events, are associated with poor outcomes in patients with various cardiovascular diseases. However, there has been no research on its prognostic implications in acute severe hypertension. This study investigated the association between D-dimer levels and long-term mortality in patients with severe acute hypertension who visited the emergency department.

Safety evaluation of curative gastrectomy for gastric cancer patients who underwent liver transplantation: a comparative study with conventional gastrectomy for gastric cancer patients.

Background: We aimed to examine the technical and oncological safety of curative gastrectomy for gastric cancer patients who underwent liver transplantation.

Methods: In this study, we compared the surgical and oncological outcomes of two groups. The first group consisted of 32 consecutive patients who underwent curative gastrectomy for gastric cancer after liver transplantation (LT), while the other group consisted of 127 patients who underwent conventional gastrectomy (CG).

Association between B-type natriuretic peptide and long-term mortality in patients with acute severe hypertension visiting the emergency department.

B-type natriuretic peptide (BNP) is a well-established prognostic factor for cardiovascular disorders. However, the association between BNP levels and mortality in patients with acute severe hypertension remains unclear. This study aimed to investigate the association between BNP levels and long-term mortality in patients with acute severe hypertension visiting the emergency department (ED).