Publications by authors named "Benjamin Marsac"

Importance: Metabolic flexibility, a key hallmark of cancer, reflects aberrant tumour changes associated with metabolites. The metabolic plasticity of pancreatic neuroendocrine tumours (pNETs) remains largely unexplored. Notably, the heterogeneity of pNETs complicates their diagnosis, prognosis, and therapeutic management.

View Article and Find Full Text PDF

Intestinal mucins play a crucial role in the mucosal barrier, serving as the body's initial defense against microorganisms. However, how the host regulates the secretion and glycosylation of these mucins in response to bacterial invasion remains unclear. Our study demonstrates that when exposed to (), a gut pathobiont, the host mucosa promptly adjusts the behavior of specialized goblet cells (GCs) located in the middle of the crypts.

View Article and Find Full Text PDF
Article Synopsis
  • Staphylococcus aureus is a bacteria that often causes lung infections, especially in people with chronic conditions.
  • Scientists found that this bacteria can use a substance called sialic acid to grow better, especially when it doesn’t work well with its signaling system (quorum sensing).
  • In patients with cystic fibrosis, researchers discovered that S. aureus often lives alongside bacteria that produce sialic acid, suggesting that sialic acid helps it become more harmful and survive longer in the lungs.
View Article and Find Full Text PDF