Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.

Background: Perioperative hemodynamic abnormalities have been associated with neurocognitive outcomes after noncardiac surgery.

Objective: To compare the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery.

Design: Randomized controlled trial.

Advances in Predictive RAHT for Geometric Point Cloud Compression.

Point cloud compression is critical for the success of immersive multimedia applications. For attribute compression in geometric point cloud compression (G-PCC), Region Adaptive Hierarchical Transform (RAHT) is the preferred coding method. This paper presents several advances to predictive coding with RAHT: 1) Sample Domain Prediction: Prediction in RAHT is done in transform domain.

Dimethyl ester of bilirubin ameliorates Naja naja snake venom-induced lung toxicity in mice via inhibiting NLRP3 inflammasome and MAPKs activation.

Naja naja snake bite causes thousands of deaths worldwide in a year. N. naja envenomed victims exhibit both local and systemic reactions that potentially lead to death.

Unconjugated bilirubin and its derivative ameliorate IMQ-induced psoriasis-like skin inflammation in mice by inhibiting MMP9 and MAPK pathway.

Psoriasis is a chronic immune-mediated inflammatory skin disease that involves dysregulated proliferation of keratinocytes. Psoriatic skin lesions are characterized by redness, thickness, and scaling. The interleukin axis of IL-23/IL-17 is critically involved in the development of human psoriasis.